Evidence map›Paper›PMID 32238432›Full record

ArticleThe Journal of biological chemistry2020

Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision.

Rebecca Ward, Joanna J Kaylor, Diego F Cobice, Dionissia A Pepe, Eoghan M McGarrigle, Susan E Brockerhoff, James B Hurley, Gabriel H Travis, Breandán N Kennedy

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Germline Disruption of Retinal Pigment Epithelium-Expressed Zebrafish rlbp1bFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Article
  3. Novel in vivo models of autosomal optic atrophy reveal conserved pathological changes in neuronal mitochondrial structure and function.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Review
  5. Proposing Zebrafish as a Model for Stargardt Disease.Advances in experimental medicine and biology · 2025
    Review
  6. Acyl-CoA:wax alcohol acyltransferase 2 modulates the cone visual cycle in mouse retina.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  7. Retinal pigment epithelium 65 kDa protein (RPE65): An update.Progress in retinal and eye research · 2022
    Review
  8. Dawn and dusk peaks of outer segment phagocytosis, and visual cycle function require Rab28.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Shedding new light on the generation of the visual chromophore.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Rebecca WardUCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Dublin D04 V1W8, Ireland.ORCID 0000-0003-2957-8642
Joanna J KaylorJules Stein Eye Institute, UCLA School of Medicine, Los Angeles, California 90095.ORCID 0000-0002-4535-2574
Diego F CobiceMass Spectrometry Centre, School of Biomedical Sciences, Biomedical Sciences Research Institute, Ulster University, Coleraine BT52 1SA, Northern Ireland.ORCID 0000-0001-5283-2931
Dionissia A PepeCentre for Synthesis and Chemical Biology, UCD School of Chemistry, University College Dublin, Dublin D04 V1W8, Ireland.ORCID 0000-0001-5401-8407
Eoghan M McGarrigleCentre for Synthesis and Chemical Biology, UCD School of Chemistry, University College Dublin, Dublin D04 V1W8, Ireland.ORCID 0000-0001-8160-6431
Susan E BrockerhoffDepartment of Biochemistry, University of Washington, Seattle, Washington 98109.ORCID 0000-0002-9851-5525
James B HurleyDepartment of Biochemistry, University of Washington, Seattle, Washington 98109.
Gabriel H TravisJules Stein Eye Institute, UCLA School of Medicine, Los Angeles, California 90095.ORCID 0000-0003-4020-9493
Breandán N KennedyUCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Dublin D04 V1W8, Ireland brendan.kennedy@ucd.ie.ORCID 0000-0001-7991-4689
University College Dublin · IEUniversity of Washington · USDoheny Eye Institute · USUniversity of California, Los Angeles · USUniversity of Ulster · GB

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xian-Jie Yang · 1985 to 2026
$16.8M
Mechanisms for Light-driven Chromophore Synthesis by Müller Cells to Regenerate Cone Opsin and Maintain Cone SensitivityR01EY024379 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TRAVIS, GABRIEL H · 2015 to 2024
$3.3M
NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY024379
6 · The paper itself

Abstract

Cone photoreceptors in the retina enable vision over a wide range of light intensities. However, the processes enabling cone vision in bright light (

Indexed as

Color VisionAnimalsCarrier Proteinscis-trans-IsomerasesEpendymoglial CellsFatty Acid DesaturasesGene DeletionRetinal Cone Photoreceptor CellsRetinoid IsomerohydrolaseVitamin AZebrafish11-cis-retinal-binding proteinCarrier Proteinscis-trans-IsomerasesFatty Acid DesaturasesRetinoid IsomerohydrolaseVitamin Achemical biologycone-based visual behaviorpharmacologyretinaRpe65visionvisual cyclevitamin Azebrafish

Identifiers

PMID32238432
PMCPMC7212626
OpenAlexW3014537025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.