Evidence map›Paper›PMID 32238077›Full record

ReviewThe British journal of radiology2020

Integrated cardiovascular assessment of atherosclerosis using PET/MRI.

Nicholas R Evans, Jason M Tarkin, Elizabeth Pv Le, Rouchelle S Sriranjan, Andrej Corovic, Elizabeth A Warburton, James Hf Rudd

Open access · greenAbstract readReview
In one paragraph

Review in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Vascular medicine (London, England) · 2025
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Carotid atherosclerotic plaque microcalcification is independently associated with recurrent neurovascular events: A pilot study.International journal of stroke : official journal of the International Stroke Society · 2024
    Article
  8. Vascular medicine in the 21World journal of clinical cases · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Hybrid positron emission tomography and magnetic resonance imaging in carotid atherosclerosis: Not ready for prime time?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  14. Review
  15. Review
  16. The Elusive Origin of Atherosclerotic Plaque Calcification.Frontiers in cell and developmental biology · 2021
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nicholas R EvansDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0002-7640-4701
Jason M TarkinDivision of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
Elizabeth Pv LeDivision of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
Rouchelle S SriranjanDivision of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
Andrej CorovicDivision of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
Elizabeth A WarburtonDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
James Hf RuddDivision of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GB

Funding

British Heart Foundation PG/09/083/27667Wellcome Trust 211100/Z/18/Z
6 · The paper itself

Abstract

Atherosclerosis is a systemic inflammatory disease typified by the development of lipid-rich atheroma (plaques), the rupture of which are a major cause of myocardial infarction and stroke. Anatomical evaluation of the plaque considering only the degree of luminal stenosis overlooks features associated with vulnerable plaques, such as high-risk morphological features or pathophysiology, and hence risks missing vulnerable or ruptured non-stenotic plaques. Consequently, there has been interest in identifying these markers of vulnerability using either MRI for morphology, or positron emission tomography (PET) for physiological processes involved in atherogenesis. The advent of hybrid PET/MRI scanners offers the potential to combine the strengths of PET and MRI to allow comprehensive assessment of the atherosclerotic plaque. This review will discuss the principles and technical aspects of hybrid PET/MRI assessment of atherosclerosis, and consider how combining the complementary modalities of PET and MRI has already furthered our understanding of atherogenesis, advanced drug development, and how it may hold potential for clinical application.

Indexed as

AtherosclerosisCarotid StenosisForecastingHumansMagnetic Resonance ImagingMultimodal ImagingPlaque, AtheroscleroticPositron-Emission TomographyPositron Emission Tomography Computed TomographyVascular Calcification

Identifiers

PMID32238077
PMCPMC7465854
OpenAlexW3014921846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.