Evidence map›Paper›PMID 32238008›Full record

SynthesisExpert opinion on drug metabolism & toxicology2020

The impact of pregnancy on the pharmacokinetics of antidepressants: a systematic critical review and meta-analysis.

Georgios Schoretsanitis, Olav Spigset, Julia C Stingl, Kristina M Deligiannidis, Michael Paulzen, Andreas A Westin

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Expert opinion on drug metabolism & toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Do sex and gender matter in the pharmacological treatment of depression?Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Changes in the pharmacokinetics of lurasidone in a pregnant woman with schizophrenia.PCN reports : psychiatry and clinical neurosciences · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Georgios SchoretsanitisThe Zucker Hillside Hospital, Department of Psychiatry Research, Northwell Health, Glen Oaks, NY, USA.ORCID https://orcid.org/0000-0002-3851-4117
Olav SpigsetDepartment of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway.
Julia C StinglInstitute of Clinical Pharmacology, University Hospital of RWTH Aachen, Aachen, Germany.
Kristina M DeligiannidisThe Zucker Hillside Hospital, Department of Psychiatry Research, Northwell Health, Glen Oaks, NY, USA.ORCID https://orcid.org/0000-0001-7439-2236
Michael PaulzenAlexianer Hospital Aachen, Aachen, Germany and Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, and JARA - Translational Brain Medicine, Aachen, Germany.ORCID https://orcid.org/0000-0003-4198-5160
Andreas A WestinDepartment of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway.
Northwell Health · USRWTH Aachen University · DENorwegian University of Science and Technology · NOSt Olav's University Hospital · NO

Funding

Personalized Integrated Chronotherapy for Perinatal DepressionR01MH118269 · NIMH · RHODE ISLAND HOSPITAL · PI SHARKEY, KATHERINE M · 2020 to 2023
$5.1M
Relationships between Neuroactive Steroids, GABA and Glutamate MRS and Connectivity of the Default Mode Network in Postpartum DepressionR01MH120313 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DELIGIANNIDIS, KRISTINA MARIE · 2020 to 2024
$2.7M
NIMH NIH HHS L30 MH104713NIMH NIH HHS R01 MH118269NIMH NIH HHS R01 MH120313
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antidepressive AgentsDepressionDose-Response Relationship, DrugFemaleHumansPregnancyPregnancy ComplicationsPregnancy Trimester, ThirdAntidepressive AgentsAntidepressantscitalopramfluoxetinegestationpharmacokineticspregnancysertralinetherapeutic drug monitoringvenlafaxinewomen’s mental health

Identifiers

PMID32238008
PMCPMC7323120
OpenAlexW3015060416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.