Evidence map›Paper›PMID 32237043›Full record

ArticleFEBS open bio2020

Astrocytes in Atp1a2-deficient heterozygous mice exhibit hyperactivity after induction of cortical spreading depression.

Hiroki Sugimoto, Masaaki Sato, Junichi Nakai, Kiyoshi Kawakami

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hiroki SugimotoDivision of Biology, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.ORCID 0000-0003-1614-6971
Masaaki SatoGraduate School of Science and Engineering, Saitama University, Japan.ORCID 0000-0002-5206-3375
Junichi NakaiGraduate School of Science and Engineering, Saitama University, Japan.ORCID 0000-0001-9963-2603
Kiyoshi KawakamiDivision of Biology, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.ORCID 0000-0002-0058-4072
Jichi Medical University · JPRIKEN Center for Brain Science · JPSaitama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ATP1A2 coding α2 subunit of Na,K-ATPase, which is predominantly located in astrocytes, is a causative gene of familial hemiplegic migraine type 2 (FHM2). FHM2 model mice (Atp1a2

Indexed as

AnimalsAstrocytesCalciumCations, DivalentCerebral CortexCortical Spreading DepressionDisease Models, AnimalFemaleHeterozygoteHumansIntravital MicroscopyMiceMice, TransgenicMicroscopy, Fluorescence, MultiphotonMigraine with AuraNeuronsAtp1a2 protein, mouseCalciumCations, DivalentSodium-Potassium-Exchanging ATPaseastrocyteAtp1a2calcium imagingCSDFHM2G-CaMP7migraine

Identifiers

PMID32237043
PMCPMC7262908
OpenAlexW3015002488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.