Evidence map›Paper›PMID 32237041›Full record

ArticleFEBS open bio2020

ASIC1a inhibits cell pyroptosis induced by acid-induced activation of rat hepatic stellate cells.

Jun Li, Lingjin Kong, Huiping Huang, Shaohua Luan, Rui Jin, Fanrong Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jun LiSchool of Pharmacy, Anhui Medical University, Hefei, China.
Lingjin KongSchool of Pharmacy, Anhui Medical University, Hefei, China.
Huiping HuangSchool of Pharmacy, Anhui Medical University, Hefei, China.
Shaohua LuanSchool of Pharmacy, Anhui Medical University, Hefei, China.
Rui JinSchool of Pharmacy, Anhui Medical University, Hefei, China.
Fanrong WuSchool of Pharmacy, Anhui Medical University, Hefei, China.ORCID 0000-0002-5073-5799
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activation of hepatic stellate cells (HSCs) is associated with liver fibrosis, the pathological feature of most forms of chronic hepatic damage, and is accompanied by abnormal deposition of the extracellular matrix (ECM). During the pathological process, acid-sensing ion channel 1a (ASIC1a), which is responsible for Ca

Indexed as

Acid Sensing Ion ChannelsAnimalsCalciumCARD Signaling Adaptor ProteinsCaspase 1Cations, DivalentCell LineDisease Models, AnimalGasderminsHepatic Stellate CellsHumansHydrogen-Ion ConcentrationIntracellular Signaling Peptides and ProteinsLiverLiver CirrhosisNLR Family, Pyrin Domain-Containing 3 ProteinAcid Sensing Ion ChannelsAsic1 protein, ratCalciumCARD Signaling Adaptor ProteinsCaspase 1Cations, DivalentGasderminsGsdmd protein, ratIntracellular Signaling Peptides and ProteinsNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, ratPhosphate-Binding ProteinsPycard protein, ratRecombinant ProteinsRNA, Small Interferingacid-sensing ion channelsASIC1ahepatic fibrosishepatic stellate cellspyroptosis

Identifiers

PMID32237041
PMCPMC7262943
OpenAlexW3014851696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.