Trial reportPharmacoepidemiology and drug safety2020
A behavioral economics-based telehealth intervention to improve aspirin adherence following hospitalization for acute coronary syndrome.
Trial report in Pharmacoepidemiology and drug safety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Methods and validity indicators for measuring adherence and persistence to aspirin in secondary cardiovascular prevention: a systematic review.Frontiers in cardiovascular medicine · 2025Pooled it
- Assessing the Impact of Behavioral Sciences Interventions on Chronic Disease Prevention and Management: A Systematic Review of Randomized Controlled Trials.International journal of environmental research and public health · 2024Pooled it
- Optimising the implementation of digital-supported interventions for the secondary prevention of heart disease: a systematic review using the RE-AIM planning and evaluation framework.BMC health services research · 2023Pooled it
- A pilot randomized clinical trial of gamification to increase medication adherence.American heart journal · 2026 · on this mapTrial
- Reminder Strategies to Improve Meal-Logging Adherence: Protocol for a Microrandomized Trial.JMIR research protocols · 2026Article
- Digital cardiac rehabilitation versus traditional cardiac rehabilitation in improving health parameters, patient satisfaction and adherence to guidelines-a systematic review and a meta-analysis.Cardiovascular diagnosis and therapy · 2026Article
- The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial.NPP - digital psychiatry and neuroscience · 2025Article
- The Jaga Diri digital intervention improved knowledge and adherence to weekly iron-folic acid supplementation among adolescent girls in Maluku Province, Indonesia.Frontiers in digital health · 2025Article
- A systematic review of the impacts of remote patient monitoring (RPM) interventions on safety, adherence, quality-of-life and cost-related outcomes.NPJ digital medicine · 2024Review
- Improving medication adherence in cardiovascular disease.Nature reviews. Cardiology · 2024Review
- Efficacy of eHealth Technologies on Medication Adherence in Patients With Acute Coronary Syndrome: Systematic Review and Meta-Analysis.JMIR cardio · 2023Review
- Digital Health Programs to Reduce Readmissions in Coronary Artery Disease: A Systematic Review and Meta-Analysis.JACC. Advances · 2023Article
- Nursing care and management of adverse events for patients with BRAFSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Review
- Applications of Behavioral Economics to Pharmaceutical Policymaking: A Scoping Review with Implications for Best-Value Biological Medicines.Applied health economics and health policy · 2022Article
- Behavioral Economics and Tobacco Control: Current Practices and Future Opportunities.International journal of environmental research and public health · 2022Article
- Patient Adherence to Therapy After Myocardial Infarction: A Scoping Review.Patient preference and adherence · 2022Article
- The Role of Behavioral Economics in Improving Cardiovascular Health Behaviors and Outcomes.Current cardiology reports · 2021Review
- Comparing medication adherence using a smartphone application and electronic monitoring among patients with acute coronary syndrome.Applied nursing research : ANR · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeA significant number of patients with acute coronary syndrome (ACS) are nonadherent to aspirin after hospital discharge, with an associated increased risk of subsequent cardiovascular events. The purpose of this pilot study was to test the efficacy of a telehealth intervention based on behavioral economics to improve aspirin adherence following hospitalization for ACS.
methodsWe enrolled 130 participants (c¯X = 58 ± 10.7 years of age, 38% female, 45% black) from two hospitals. Patients were eligible if they owned a smartphone and were admitted to the hospital for ACS, prescribed aspirin at discharge, and responsible for administering their own medications. Consenting participants were randomized to the intervention or usual care group. The intervention group was eligible to receive up to $50 per month if they took their medicine daily, with $2 per day deducted if a dose was missed. All participants received an electronic monitoring (EM) pill bottle containing a 90-day supply of aspirin, which was used to measure adherence calculated as the proportion of prescribed drug taken using the EM device. Based on the skewness in the adherence distribution, quantile regression was used to evaluate the effect of the intervention on median adherence over time.
resultsAfter 90 days, adherence fell in the control group but remained high in the intervention group (median adherence 81% vs 90%, P = .18). Rehospitalization was higher in the control group (24% vs 13%, P = .17).
conclusionA loss aversion behavioral economics-based telehealth intervention is a promising approach to improving aspirin adherence following hospitalization for ACS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.