Evidence map›Paper›PMID 32236984›Full record

ArticleMolecular microbiology2020

LptB-LptF coupling mediates the closure of the substrate-binding cavity in the LptB

Emily A Lundstedt, Brent W Simpson, Natividad Ruiz

Open access · greenAbstract read
In one paragraph

Article in Molecular microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The LptC transmembrane helix undergoes a rigid body movement upon LptBProtein science : a publication of the Protein Society · 2025
    Article
  5. Article
  6. Residues within the LptC transmembrane helix are critical for Escherichia coli LptBProtein science : a publication of the Protein Society · 2024
    Article
  7. ABC Transporters in Bacterial Nanomachineries.International journal of molecular sciences · 2023
    Review
  8. Lipid Transport Across Bacterial Membranes.Annual review of cell and developmental biology · 2022
    Review
  9. Article
  10. Review
  11. Cardiolipin aids in lipopolysaccharide transport to the gram-negative outer membrane.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emily A LundstedtDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.
Brent W SimpsonDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.
Natividad RuizDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-6369-2206
The Ohio State University · US

Funding

Envelope Biogenesis in Gram-negative BacteriaR01GM100951 · NIGMS · OHIO STATE UNIVERSITY · PI RUIZ, NATIVIDAD · 2012 to 2023
$3.7M
NIGMS NIH HHS R01 GM100951
6 · The paper itself

Abstract

Lipopolysaccharides (LPS) are essential envelope components in many Gram-negative bacteria and provide intrinsic resistance to antibiotics. LPS molecules are synthesized in the inner membrane and then transported to the cell surface by the LPS transport (Lpt) machinery. In this system, the ATP-binding cassette (ABC) transporter LptB

Indexed as

Adenosine TriphosphatasesATP-Binding Cassette TransportersBiological TransportCell MembraneEscherichia coliEscherichia coli ProteinsLipopolysaccharidesMembrane ProteinsMembrane Transport ProteinsPeriplasmAdenosine TriphosphatasesATP-Binding Cassette TransportersEscherichia coli Proteinsinner membrane protein, E coliLipopolysaccharidesLptB protein, E coliLptF protein, E coliLptG protein, E coliMembrane ProteinsMembrane Transport ProteinsABC transporters (D018528)acyltransferases (D000217)cell membrane permeability (D002463)Escherichia coli K-12 (D048168)lipopolysaccharides (D008070)membrane transport proteins (D026901)

Identifiers

PMID32236984
PMCPMC7529706
OpenAlexW3014833039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.