Evidence map›Paper›PMID 32236891›Full record

ArticlePharmacoEconomics2020

R and Shiny for Cost-Effectiveness Analyses: Why and When? A Hypothetical Case Study.

Rose Hart, Darren Burns, Bram Ramaekers, Shijie Ren, Daniel Gladwell, Will Sullivan, Niall Davison, Owain Saunders, Indeg Sly, Theresa Cain and 1 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in PharmacoEconomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Treatments for renal cell carcinoma: NICE Pilot Treatment Pathways Appraisal.Health technology assessment (Winchester, England) · 2026
    Pooled it
  2. Pooled it
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rose HartBresMed Health Solutions, Sheffield, UK. rhart@bresmed.com.ORCID http://orcid.org/0000-0001-7302-2559
Darren BurnsBresMed Health Solutions, Sheffield, UK.ORCID http://orcid.org/0000-0002-5209-8041
Bram RamaekersDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0001-5785-9228
Shijie RenSchool of Health and Related Research, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0003-3568-7124
Daniel GladwellBresMed Health Solutions, Sheffield, UK.
Will SullivanBresMed Health Solutions, Sheffield, UK.ORCID http://orcid.org/0000-0001-5221-7074
Niall DavisonBresMed Health Solutions, Manchester, UK.ORCID http://orcid.org/0000-0002-9447-0825
Owain SaundersBresMed Health Solutions, Manchester, UK.
Indeg SlyBresMed Health Solutions, Sheffield, UK.
Theresa CainBresMed Health Solutions, Sheffield, UK.
Dawn LeeBresMed Health Solutions, Sheffield, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHealth economics models are typically built in Microsoft Excel

objectiveThis case study provides an explicit comparison between Excel and R for contemporary cost-effectiveness analysis.

methodsWe constructed duplicate cost-effectiveness models using Excel and R (with a user interface built using the Shiny package) to address a hypothetical case study typical of contemporary health technology assessment.

resultsWe compared R and Excel versions of the same model design to determine the advantages and limitations of the modelling platforms in terms of (i) analytical capability, (ii) data safety, (iii) building considerations, (iv) usability for technical and non-technical users and (v) model adaptability.

conclusionsThe findings of this explicit comparison are used to produce recommendations for when R might be more suitable than Excel in contemporary cost-effectiveness analyses. We conclude that selection of appropriate modelling software needs to consider case-by-case modelling requirements, particularly (i) intended audience, (ii) complexity of analysis, (iii) nature and frequency of updates and (iv) anticipated model run time.

Indexed as

Cost-Benefit AnalysisModels, EconomicOutcome Assessment, Health CareDrug IndustryHumansSoftwareTechnology Assessment, Biomedical

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.