ArticleJournal of natural medicines2020
Induction of secondary metabolite production by fungal co-culture of Talaromyces pinophilus and Paraphaeosphaeria sp.
Article in Journal of natural medicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- A mass spectrometry-based strategy for investigating volatile molecular interactions in microbial consortia: unveiling aFrontiers in microbiology · 2024Article
- Review
- Bioactive compounds and biomedical applications of endophytic fungi: a recent review.Microbial cell factories · 2023Review
- The Potential Use of Fungal Co-Culture Strategy for Discovery of New Secondary Metabolites.Microorganisms · 2023Review
- Fungal-fungal co-culture: a primer for generating chemical diversity.Natural product reports · 2022Review
- Review
- The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade.Drug design, development and therapy · 2022Review
- Cryptic Biosynthesis of the Berkeleypenostatins from Coculture of ExtremophilicJournal of natural products · 2021Article
- Multifarious Elicitors: Invoking Biosynthesis of Various Bioactive Secondary Metabolite in Fungi.Applied biochemistry and biotechnology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Fungal co-culture is a strategy to induce the production of secondary metabolites by activating cryptic genes. We discovered the production of a new compound, talarodone A (1), along with five known compounds 2-6 in co-culture of Talaromyces pinophilus and Paraphaeosphaeria sp. isolated from soil collected in Miyazaki Prefecture, Japan. Among them, the productions of penicidones C (2) and D (3) were enhanced 27- and sixfold, respectively, by the co-culture. The structure of 3 should be represented as a γ-pyridol form with the reported chemical shifts, but not as a γ-pyridone form, based on DFT calculation.
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Registered trials
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