Evidence map›Paper›PMID 32236818›Full record

Trial reportEndocrine2020

The effects of nigella sativa on anthropometric and biochemical indices in postmenopausal women with metabolic syndrome.

Mahboobeh Shirazi, Fatemeh Khodakarami, Elham Feizabad, Marjan Ghaemi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Endocrine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effect ofCurrent medicinal chemistry · 2025
    Pooled it
  2. Review
  3. Analysis of Pharmacological Properties ofLife (Basel, Switzerland) · 2025
    Review
  4. The Use ofBiomedicines · 2024
    Review
  5. Article
  6. Review
  7. IsVascular health and risk management · 2022
    Review
  8. Black Cumin (Nutrients · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahboobeh ShiraziMaternal, Fetal & Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-3515-4985
Fatemeh KhodakaramiMaternal, Fetal & Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran.
Elham FeizabadMaternal, Fetal & Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-0372-5897
Marjan GhaemiMaternal, Fetal & Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran. marjan_ghaemi@yahoo.com.ORCID 0000-0003-2306-7112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to compare the nigella sativa vs. placebo effect on anthropometric and biochemical indices in postmenopausal women with metabolic syndrome.

methodsThis randomized, double-blinded, placebo-controlled trial was conducted as a third-phase trial among 140 menopausal women within the age of 45-60 years old, who were suffering from metabolic syndrome and were assigned to receive 500 mg nigella sativa or placebo pill once daily. Anthropometric and biochemical parameters including body weight, waist circumference, serum lipid profile, fasting blood sugar, and HbA1C were measured at baseline and 8 weeks after administration the ingredient or placebo.

resultsIn nigella sativa group, the serum markers such as low-density lipoprotein (115.1 ± 17.6 vs. 127.7 ± 12.6), triglyceride (158.3 ± 14.0 vs. 166.7 ± 16.0), total cholesterol (115.1 ± 17.6 vs. 127.7 ± 12.6), and fasting blood sugar (90.8 ± 16.9 vs. 113.7 ± 12.1) decreased significantly compared with the placebo (p < 0.001).

conclusionAdministration of nigella sativa might be recommended for improving lipid profile and blood sugar in postmenopausal women with the metabolic syndrome.

Indexed as

Metabolic SyndromeNigella sativaAnthropometryBody WeightFemaleHumansMiddle AgedPostmenopauseMenopauseMetabolic syndromeNigella sativa

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.