ArticleWorld journal of urology2021
The role of vacuum-assisted closure (VAC) therapy in the management of FOURNIER'S gangrene: a retrospective multi-institutional cohort study.
Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Vacuum-assisted closure versus conventional dressing in necrotizing fasciitis: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Vacuum-assisted closure device in the postoperative wound care for Fournier's gangrene: a systematic review.International urology and nephrology · 2021Pooled it
- Outcomes of vacuum-assisted closure therapy (VAC) in patients with Fournier's gangrene: a retrospective cohort study.Irish journal of medical science · 2026Article
- Negative pressure wound therapy for perianal necrotizing fasciitis: case report and literature review.Frontiers in surgery · 2026Article
- Fournier's Gangrene in Neonates: A Case Report and Literature Review.Journal of plastic and reconstructive surgery · 2025Article
- Paediatric Fournier gangrene: comprehensive insights into diagnosis, management, and outcomes-a narrative review.Translational pediatrics · 2025Review
- The role of double-lumen irrigation-suction tube in the treatment of disseminated Fournier's gangrene: a single-center retrospective cohort study.Translational andrology and urology · 2025Article
- Article
- Successful Treatment of Fournier's Gangrene in Child with Relapsed Acute Lymphoblastic Leukemia: Case Report and Review of the Literature.Infection and drug resistance · 2025Article
- Fournier's Gangrene Surgical Reconstruction: A Systematic Review.Journal of clinical medicine · 2024Review
- Fournier's gangrene due to rectal cancer: A case report.Molecular and clinical oncology · 2024Article
- Diagnostic Key Points and Surgical Management of Necrotizing Fasciitis: A Retrospective Study.The international journal of lower extremity wounds · 2024Article
- Comprehensive management and outcomes in female patients with Fournier's gangrene: A case report.SAGE open medical case reports · 2024Article
- Evaluation of Negative Pressure Wound Therapy in the Management of Fournier's Gangrene.Cureus · 2023Article
- Vacuum sealing drainage to treat Fournier's gangrene.BMC surgery · 2023Article
- What Has Changed in the History of Fournier's Gangrene Treatment: The Single-Center Experience.Sisli Etfal Hastanesi tip bulteni · 2023Article
- Bibliometric insights in fournier's gangrene: Research landscapes, turning points, and global trends.Frontiers in surgery · 2023Review
- Contralateral necrotizing fascitis after left nephrectomy for emphysematous pyelonephritis.IJU case reports · 2022Article
- Negative Pressure Wound Therapy for the Treatment of Fournier's Gangrene: A Rare Case with Rectal Fistula and Systematic Review of the Literature.Journal of personalized medicine · 2022Review
- Our experience on Fournier's gangrene in a tertiary-stage care center and analysis of its relationship with blood count parameters.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
Corrections and comments
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Authors and funding
24 authors at 13 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo explore the role of vacuum assisted closure (VAC) therapy versus conventional dressings in the Fournier's gangrene wound therapy. PATIENTS AND
methodsThis is a retrospective multi-institutional cohort study. Data of 92 patients from nine centers between 2007 and 2018 were retrospectively analyzed. After surgery, patient having a local or a disseminated FG were managed with VAC therapy or with conventional dressings. The 10-weeks wound closure cumulative rate and OS were analyzed.
resultsOf the 92 patients, 62 (67.4%) showed local and 30 (32.6%) a disseminated FG. After surgery, 19 patients (20.7%) with local and 14 (15.2%) with disseminated FG underwent to VAC therapy; 43 (46.7%) with local and 16 (17.4%) with disseminated FG were treated using conventional dressings. The multivariable logistic regression analysis demonstrated that the VAC in patients with disseminated FG led to a higher cumulative rate of wound closure than patients treated with no-VAC (OR = 6.5; 95% CI 1.1-37.4, p = 0.036). The Kaplan-Meier survival curves for the OS showed a significant difference between no-VAC patients with local and disseminated FG (OS rate at 90 days 0.90, 95% CI 0.71-0.97 vs 0.55, 95% CI 0.24-0.78, respectively; p = 0.039). Cox regression confirmed that no-VAC patients with disseminated FG showed the lowest OS (hazard ratio adjusted for sex and age HR = 3.4, 95% CI 1.1-10.4; p = 0.033).
conclusionsIn this large cohort study, VAC therapy in patients with disseminated FG may offer an advantage in terms of 10-weeks wound closure cumulative rate and OS at 90 days after initial surgery.
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