Evidence map›Paper›PMID 32236562›Full record

Trial reportJournal of molecular cell biology2020

Treating COVID-19 with Chloroquine.

Mingxing Huang, Tiantian Tang, Pengfei Pang, Man Li, Ruolan Ma, Jiahui Lu, Jingxian Shu, Yingying You, Binghui Chen, Jiabi Liang and 8 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of molecular cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 21 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed, 21 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 21 syntheses or guidelines pooled it.

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  4. Chloroquine or hydroxychloroquine for prevention and treatment of COVID-19.The Cochrane database of systematic reviews · 2021
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  13. Clinical evidence for repurposing chloroquine and hydroxychloroquine as antiviral agents: a systematic review.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
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  15. A Rapid Systematic Review of Clinical Trials Utilizing Chloroquine and Hydroxychloroquine as a Treatment for COVID-19.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2020
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75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Mingxing HuangDepartment of Infectious Diseases, The Fifth Affiliated Hospital, Sun Yat-sen University (SYSU), Zhuhai 519000, China.
Tiantian TangDepartment of Respiratory and Critical Care Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Pengfei PangGuangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Man LiGuangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Ruolan MaGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Jiahui LuDepartment of Infectious Diseases, The Fifth Affiliated Hospital, Sun Yat-sen University (SYSU), Zhuhai 519000, China.
Jingxian ShuDepartment of Pharmacy, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Yingying YouDepartment of Stomatology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Binghui ChenDepartment of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Jiabi LiangDepartment of Pharmacy, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Zhongsi HongDepartment of Infectious Diseases, The Fifth Affiliated Hospital, Sun Yat-sen University (SYSU), Zhuhai 519000, China.
Huili ChenDepartment of Infectious Diseases, The Fifth Affiliated Hospital, Sun Yat-sen University (SYSU), Zhuhai 519000, China.
Ling KongGuangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510700, China.
Dajiang QinGuangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510700, China.
Duanqing PeiGuangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510700, China.
Jinyu XiaDepartment of Infectious Diseases, The Fifth Affiliated Hospital, Sun Yat-sen University (SYSU), Zhuhai 519000, China.
Shanping JiangDepartment of Respiratory and Critical Care Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Hong ShanGuangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultBetacoronavirusChloroquineCoronavirus InfectionsCOVID-19Drug CombinationsHumansLopinavirMiddle AgedPandemicsPneumonia, ViralRitonavirSARS-CoV-2ChloroquineDrug CombinationsLopinavirlopinavir-ritonavir drug combinationRitonavir

Identifiers

PMID32236562
PMCPMC7232130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.