Evidence map›Paper›PMID 32236496›Full record

ArticleThe Journal of experimental medicine2020

Competence against insufficiency: Why are men mostly safe from a rare and deadly prostate cancer?

Grinu Mathew, Lloyd C Trotman

Abstract readComment
In one paragraph

Article in The Journal of experimental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Grinu MathewCold Spring Harbor Laboratory, Cold Spring Harbor, NY.
Lloyd C TrotmanCold Spring Harbor Laboratory, Cold Spring Harbor, NY.

Funding

Mechanisms and Treatment of PTEN Mutant Prostate TumorigenesisR01CA137050 · NCI · COLD SPRING HARBOR LABORATORY · PI TROTMAN, LLOYD C · 2010 to 2018
$3.1M
NCI NIH HHS R01 CA137050
6 · The paper itself

Abstract

Prostate cancer is a slow-growing disease, but not always. A highly rare and lethal form of the disease shows survival rates of less than a year. It is called squamous cell prostate carcinoma. In this issue of JEM, Hermanova et al. (https://doi.org/10.1084/jem.20191787) provide new findings in mouse demonstrating a strong genetic handle on both the reasons behind the rarity and the aggressiveness.

Indexed as

Carcinoma, Squamous CellProstatic NeoplasmsAnimalsHumansMaleMice

Identifiers

PMID32236496
PMCPMC7971130

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.