Speculation is not evidence: antihypertensive therapy and COVID-19.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Increased risk of acute kidney injury in coronavirus disease patients with renin-angiotensin-aldosterone-system blockade use: a systematic review and meta-analysis.Scientific reports · 2021
   Pooled it
2. Renin-angiotensin system inhibition and risk of infection and mortality in COVID-19: a systematic review and meta-analysis.Internal medicine journal · 2020
   Pooled it
3. SARS-CoV-2 receptor networks in diabetic and COVID-19-associated kidney disease.Kidney international · 2020
   Article
4. Risk factors associated with disease aggravation among 126 hospitalized patients with COVID-19 in different places in China: A retrospective observational study.Medicine · 2020
   Observational
5. Very low reporting rate of connective tissue diseases among coronavirus disease 2019 (Covid-19) patients and the renin-angiotensin system - An overlooked association?European journal of internal medicine · 2020
   Article
6. Can COVID 2019 induce a specific cardiovascular damage or it exacerbates pre-existing cardiovascular diseases?Pathology, research and practice · 2020
   Review
7. Related molecular mechanisms of COVID-19, hypertension, and diabetes.American journal of physiology. Endocrinology and metabolism · 2020
   Article
8. Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence.Journal of clinical medicine · 2020
   Review
9. Cardiac complications in community-acquired pneumonia and COVID-19.African journal of thoracic and critical care medicine · 2020
   Review
10. Brief review: Cardiac complications and platelet activation in COVID-19 infection.African journal of thoracic and critical care medicine · 2020
    Review

Corrections and comments

• Comment on
  Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?2020

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as