ArticlePloS one2020
Wide area spray of bacterial larvicide, Bacillus thuringiensis israelensis strain AM65-52, integrated in the national vector control program impacts dengue transmission in an urban township in Sibu district, Sarawak, Malaysia.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effectiveness of natural predators, microbial bioinsecticides, and plant-based bioinsecticides to reduce mosquito-borne disease burden: a systematic review.Journal of medical entomology · 2026Pooled it
- Systematic review of Aedes aegypti control trials suggests publication bias related to author disclosure of conflicts of interest.PLoS neglected tropical diseases · 2026Pooled it
- A Systematic Review of Mathematical Models of Dengue Transmission and Vector Control: 2010-2020.Viruses · 2023Pooled it
- Development of an eco-friendly RNAi yeast attractive targeted sugar bait that silences the shaker gene in spotted-wing drosophila, Drosophila suzukii.Pest management science · 2026Article
- Review
- Article
- Larviciding for malaria control and elimination in Africa.Malaria journal · 2025Review
- Integrated One Health strategies in Dengue.One health (Amsterdam, Netherlands) · 2024Review
- Field evaluation of WALS truck-mounted A1 super duty mist sprayer® with VectoBac® WDG againstSN applied sciences · 2022Article
- Review
- An evaluation of Bacillus thuringiensis israelensis (AM65-52) treatment for the control of Aedes aegypti using vehicle-mounted WALS® application in a densely populated urban area of Puerto Rico.Pest management science · 2021Article
- Insecticide resistance in dengue vectors from hotspots in Selangor, Malaysia.PLoS neglected tropical diseases · 2021Article
- Long-lasting microbial larvicides for controlling insecticide resistant and outdoor transmitting vectors: a cost-effective supplement for malaria interventions.Infectious diseases of poverty · 2020Article
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7 authors.
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Abstract
Several sites, Z-7L, Z-5 and Z-14, in Sibu district, Sarawak, Malaysia, experienced intense dengue transmission in 2014 that continued into 2015. A pilot study with Bacillus thuringiensis israelensis (Bti) to control Aedes aegypti (L.) and Ae. albopictus (Skuse) was evaluated in Z-7L, a densely populated site of 12 ha. Bti treatments were conducted weekly from epidemiology week (EW) 24/2015 for 4 weeks, followed by fortnight treatments for 2 months, in addition to the routine control activities. Bti was directly introduced into potable containers and the outdoor artificial and natural containers were treated via a wide area spray application method using a backpack mister. Aedes indices significantly reduced during the treatment and post treatment phases, compared to the control site, Z-5 (p<0.05). A 51 fold reduction in the incidence rate per 100,000 population (IR) was observed, with one case in 25 weeks (EW 29-52). In Z-5 and Z-14, control sites, a 6 fold reduction in the IR was observed from EW 29-52. However, almost every week there were dengue cases in Z-14 and until EW 44 in Z-5. In 2016, dengue cases resurfaced in Z-7L from EW 4. Intensive routine control activities were conducted, but the IR continued to escalate. The wide area Bti spray misting of the outdoor containers was then included from EW 27 on fortnight intervals. A 6 fold reduction in IR was observed in the Bti treatment phase (EW 32-52) with no successive weekly cases after EW 37. However, in the control sites, there were dengue cases throughout the year from EW 1-52, particularly in Z-14. We feel that the wide area Bti spray application method is an integral component in the control program, in conjunction with other control measures carried out, to suppress the vector population in outdoor cryptic containers and to interrupt the disease transmission.
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