ArticleOptics letters2020
LED array reflectance microscopy for scattering-based multi-contrast imaging.
Article in Optics letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Micro-Gap Weld Seam Contrast Enhancement via Phase Contrast Imaging.Materials (Basel, Switzerland) · 2025Article
- Sperm quality analyzer: A portable LED array microscope with dark-field imaging.Bioengineering & translational medicine · 2024Article
- Single-cell cytometry via multiplexed fluorescence prediction by label-free reflectance microscopy.Science advances · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
LED array microscopy is an emerging platform for computational imaging with significant utility for biological imaging. Existing LED array systems often exploit transmission imaging geometries of standard brightfield microscopes that leave the rich backscattered field undetected. This backscattered signal contains high-resolution sample information with superb sensitivity to subtle structural features that make it ideal for biological sensing and detection. Here, we develop an LED array reflectance microscope capturing the sample's backscattered signal. In particular, we demonstrate multimodal brightfield, darkfield, and differential phase contrast imaging on fixed and living biological specimens including Caenorhabditis elegans (C. elegans), zebrafish embryos, and live cell cultures. Video-rate multimodal imaging at 20 Hz records real time features of freely moving C. elegans and the fast beating heart of zebrafish embryos. Our new reflectance mode is a valuable addition to the LED array microscopic toolbox.
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Registered trials
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