ArticleScientific reports2020
Genome-wide identification and expression analysis of the CBF/DREB1 gene family in lettuce.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Responses of rice plant to multiple abiotic stresses revealed by transcriptome meta-analysis and identification of novel genetic factors.Scientific reports · 2025Pooled it
- Abiotic Stress in Crop Production.International journal of molecular sciences · 2023Pooled it
- Genome-wide analysis of AP2/ERF gene family in Camellia oleifera and its potential roles in ethylene-induced fruit abscission.BMC plant biology · 2026Article
- Targeted Gene Modification ofInternational journal of molecular sciences · 2026Article
- Comparative genome-wide characterization and evolutionary insights into the AP2/ERF gene family in three Coffea species (C. canephora, C. eugenioides, and C. arabica).BMC genomics · 2025Article
- Genome-wide analysis of the CBF gene family and their transcriptional response to cold stress in Hibiscus mutabilis.Scientific reports · 2025Article
- Combined enhancement of ascorbic acid, β-carotene and zeaxanthin in gene-edited lettuce.Plant biotechnology journal · 2025Article
- Functional Characterization of Pomegranate CAMTA3 in Cold Stress Responses.Plants (Basel, Switzerland) · 2025Article
- Genome-Wide Identification and In Silico Expression Analysis ofPlants (Basel, Switzerland) · 2025Article
- Genetic basis of phenotypic diversity inFrontiers in genetics · 2025Article
- Identification of DREB gene family in foxtail millet (Frontiers in plant science · 2025Article
- Article
- Advance in the Thermoinhibition of Lettuce (Plants (Basel, Switzerland) · 2024Review
- Integrated transcriptomic and metabolomic analysis provides insights into cold tolerance in lettuce (Lactuca sativa L.).BMC plant biology · 2024Article
- Low frequency of the wild-type freezing-tolerance LsCBF7 allele among lettuce population suggests a negative selection during domestication and breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Harnessing the diversity of a lettuce wild relative to identify anthocyanin-related genes transcriptionally responsive to drought stress.Frontiers in plant science · 2024Article
- Genome-Wide Identification of the CBF Gene Family and ICE Transcription Factors in Walnuts and Expression Profiles under Cold Conditions.International journal of molecular sciences · 2023Article
- Genome-wide characterization and evolutionary analysis of the AP2/ERF gene family in lettuce (Lactuca sativa).Scientific reports · 2023Article
- Identification and characterization of Glycolate oxidase gene family in garden lettuce (Lactuca sativa cv. 'Salinas') and its response under various biotic, abiotic, and developmental stresses.Scientific reports · 2023Article
- Two-step model of paleohexaploidy, ancestral genome reshuffling and plasticity of heat shock response in Asteraceae.Horticulture research · 2023Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The C-repeat binding factor (CBF)/dehydration-responsive element binding (DREB1) proteins play a prominent role in freezing tolerance and are highly conserved in higher plants. Here we performed a genome-wide search of the CBF/DREB1 gene family in lettuce (Lactuca sativa L.) and identified 14 members of the family with one member gene containing a non-sense mutation within the AP2 DNA-binding domain. A comprehensive phylogenetic analysis of the CBF/DREB1 family members in 20 plant species from the Asterid or Rosid clade provided evidence that tandem duplication played an important role in the expansion of the CBF/DREB1 family. Expression analysis showed that twelve of the lettuce CBF genes were responsive to low temperature (4 °C), and that three and six of them could also be responsive to salt and heat stresses, respectively. Unlike Arabidopsis thaliana whose members of the CBF/DREB1 family respond only to a particular stress, lettuce CBFs provide wider protection from combinations of abiotic stresses. A global transcriptome analysis revealed distinctive temporal expression patterns among the cold-regulated genes in lettuce plants exposed to low temperature. Genes induced throughout the cold treatment are enriched in functions associated with protection from UV and high-light intensity and the genes suppressed after 7 days of cold exposure are enriched in photosynthesis-associated functions. These results provide insight into the molecular evolutionary properties of the CBF/DREB1 gene family in lettuce and a reference for genetic improvement of the lettuce response to cold acclimation.
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