Evidence map›Paper›PMID 32235817›Full record

ArticleCancers2020

Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer.

Kimi Drobin, Michal Marczyk, Martin Halle, Daniel Danielsson, Anna Papiez, Traimate Sangsuwan, Annika Bendes, Mun-Gwan Hong, Ulrika Qundos, Mats Harms-Ringdahl and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. The effects of myofascial induction therapy in survivors of head and neck cancer: a randomized, controlled clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Radiotherapy resistance: identifying universal biomarkers for various human cancers.Journal of cancer research and clinical oncology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Kimi DrobinAffinity Proteomics, Science for Life Laboratory, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Tomtebodavägen 23, 171 65 Stockholm, Sweden.
Michal MarczykYale Cancer Center, Department of Internal Medicine, Yale University School of Medicine, 06511 New Haven, CT, USA.ORCID 0000-0003-2508-5736
Martin HalleDepartment of Molecular Medicine and Surgery, Karolinska Institutet, 17176, Stockholm, Sweden.
Daniel DanielssonDepartment of Clinical Science, Intervention and Technology, Division of ENT Diseases, Karolinska Institutet, 14186 Stockholm, Sweden.ORCID 0000-0001-9407-2774
Anna PapiezDepartment of Data Science and Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0003-0179-1302
Traimate SangsuwanCentre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute Stockholm University, 10691 Stockholm, Sweden.ORCID 0000-0003-4051-8376
Annika BendesAffinity Proteomics, Science for Life Laboratory, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Tomtebodavägen 23, 171 65 Stockholm, Sweden.ORCID 0000-0001-9329-2353
Mun-Gwan HongAffinity Proteomics, Science for Life Laboratory, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Tomtebodavägen 23, 171 65 Stockholm, Sweden.ORCID 0000-0001-8603-8293
Ulrika QundosAffinity Proteomics, Science for Life Laboratory, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Tomtebodavägen 23, 171 65 Stockholm, Sweden.
Mats Harms-RingdahlCentre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute Stockholm University, 10691 Stockholm, Sweden.
Peter WersällDepartment of Radiotherapy, Karolinska University Hospital, 17176 Stockholm, Sweden.
Joanna PolanskaDepartment of Data Science and Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0001-8004-9864
Jochen M SchwenkAffinity Proteomics, Science for Life Laboratory, Department of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Tomtebodavägen 23, 171 65 Stockholm, Sweden.ORCID 0000-0001-8141-8449
Siamak HaghdoostCentre for Radiation Protection Research, Department of Molecular Biosciences, The Wenner-Gren Institute Stockholm University, 10691 Stockholm, Sweden.ORCID 0000-0002-2867-4774
Science for Life Laboratory · SEKarolinska University Hospital · SESilesian University of Technology · PLStockholm University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nearly half of all cancers are treated with radiotherapy alone or in combination with other treatments, where damage to normal tissues is a limiting factor for the treatment. Radiotherapy-induced adverse health effects, mostly of importance for cancer patients with long-term survival, may appear during or long time after finishing radiotherapy and depend on the patient's radiosensitivity. Currently, there is no assay available that can reliably predict the individual's response to radiotherapy. We profiled two study sets from breast (

Indexed as

biomarkerbreast cancerhead-and-neck cancerionizing radiationmandibular osteoradionecrosispersonalized radiotherapyplasma proteinspredictionradiosensitivityradiotherapyradiotherapy side effectsskin reaction

Identifiers

PMID32235817
PMCPMC7140105
OpenAlexW3012933389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.