Evidence map›Paper›PMID 32235770›Full record

ArticleCancers2020

Upregulation of Protein Synthesis and Proteasome Degradation Confers Sensitivity to Proteasome Inhibitor Bortezomib in Myc-Atypical Teratoid/Rhabdoid Tumors.

Huy Minh Tran, Kuo-Sheng Wu, Shian-Ying Sung, Chun Austin Changou, Tsung-Han Hsieh, Yun-Ru Liu, Yen-Lin Liu, Min-Lan Tsai, Hsin-Lun Lee, Kevin Li-Chun Hsieh and 14 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 2 countries.

Huy Minh TranInternational Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0003-3145-1325
Kuo-Sheng WuGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Shian-Ying SungThe Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-0078-3899
Chun Austin ChangouThe Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Tsung-Han HsiehJoint Biobank, Office of Human Research, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-2268-9246
Yun-Ru LiuJoint Biobank, Office of Human Research, Taipei Medical University, Taipei 110, Taiwan.
Yen-Lin LiuDepartment of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Min-Lan TsaiDepartment of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Hsin-Lun LeeDepartment of Radiation Oncology, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan.
Kevin Li-Chun HsiehDepartment of Medical Imaging, Taipei Medical University Hospital, Taipei 110, Taiwan.ORCID 0000-0001-7725-9019
Wen-Chang HuangDepartment of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.
Muh-Lii LiangDivision of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Hsin-Hung ChenDivision of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0001-7531-9188
Yi-Yen LeeDivision of Pediatric Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Shih-Chieh LinDepartment of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Donald Ming-Tak HoDepartment of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Feng-Chi ChangDepartment of Radiology, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Meng-En ChaoGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Wan ChenGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Shing-Shung ChuGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Alice L YuInstitute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0003-2444-0505
Yun YenThe Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology and Academia Sinica, Taipei Medical University, Taipei 110, Taiwan.
Che-Chang ChangThe Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-8080-2094
Tai-Tong WongGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0003-4075-6227
Taipei Medical University · TWTaipei Medical University Hospital · TWTaipei Veterans General Hospital · TWChang Gung University · TWUniversity of Medicine and Pharmacy at Ho Chi Minh City · VNWan Fang Hospital · TW

Funding

Ministry of Health and Welfare MOHW108-TDU-B-212-124010Ministry of Science and Technology MOST 108-2314-B-038-061-MY3Taipei Medical University Hospital 107TMU-TMUH-06Taipei Medical University Hospital 108TMU-TMUH-09
6 · The paper itself

Abstract

Atypical teratoid rhabdoid tumors (ATRTs) are among the most malignant brain tumors in early childhood and remain incurable. Myc-ATRT is driven by the

Indexed as

bortezomibMyc-ATRTsp53proteasome degradationprotein synthesis

Identifiers

PMID32235770
PMCPMC7140067
OpenAlexW3012747391

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.