Evidence map›Paper›PMID 32235735›Full record

ArticlePolymers2020

Bio-Nanocomposite Hydrogel Based on Zinc Alginate/Graphene Oxide: Morphology, Structural Conformation, Thermal Behavior/Degradation, and Dielectric Properties.

Roser Sabater I Serra, José Molina-Mateo, Constantino Torregrosa-Cabanilles, Andreu Andrio-Balado, José María Meseguer Dueñas, Ángel Serrano-Aroca

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Amine-Functionalized NiCoFeInternational journal of nanomedicine · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Alginate: Enhancement Strategies for Advanced Applications.International journal of molecular sciences · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Roser Sabater I SerraCentre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, 46022 València, Spain.ORCID 0000-0002-5550-7066
José Molina-MateoCentre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, 46022 València, Spain.
Constantino Torregrosa-CabanillesCentre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, 46022 València, Spain.
Andreu Andrio-BaladoDepartament de Física, Universitat Jaume I, 12071 Castelló, Spain.
José María Meseguer DueñasCentre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, 46022 València, Spain.ORCID 0000-0001-7518-7971
Ángel Serrano-ArocaBiomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, 46001 València, Spain.ORCID 0000-0002-9953-3848
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESUniversitat Politècnica de València · ESUniversitat Jaume I · ESValencia Catholic University Saint Vincent Martyr · ES

Funding

Fundación Universidad Católica de Valencia San Vicente Mártir 2019-231-003UCVthe Spanish Ministry of Science, Innovations and Universities (including the FEDER financial support) RTI2018-097862-B-C21 Project
6 · The paper itself

Abstract

Bio-nanocomposite hydrogels based on sodium alginate (SA) as polymer matrix and graphene oxide (GO) nanosheets with zinc as crosslinking agent were synthesized with the aim of incorporating the intrinsic properties of their constituents (bioactivity and antimicrobial activity). Thus, stable and highly interconnected networks were obtained from GO nanosheets dispersed in SA matrices through interactions with low amounts of zinc. The GO nanosheets were successfully incorporated into the alginate matrix in the form of a complex nano-network involving different interactions: Bonds between alginate chains induced by Zn ions (egg box structure), interactions between GO nanosheets through Zn ions and hydrogen bonds between alginate chains, and GO nanosheets. The molecular interactions and morphology were confirmed by Fourier-transform infrared spectroscopy and transmission electron microscopy. The composite's structural organization showed enhanced thermal stability. The glass transition temperature shifted to a higher temperature due to the reduced mobility induced by additional crosslinking bonds after incorporating the GO nanosheets and Zn into the polymer matrix. Finally, the dielectric behavior revealed that charge carrier mobility was hampered by the compact structure of the nanonetwork, which reduced conductivity. The combined properties of these nanocomposite hydrogels make them attractive biomaterials in the field of regenerative medicine and wound care since both surface bioactivity and antibacterial behavior are two critical factors involved in the success of a biomaterial.

Indexed as

alginatebioactivitybiocidal effectgraphene oxidehydrogelnanocompositethermal and dielectric propertiestissue engineeringzinc

Identifiers

PMID32235735
PMCPMC7183265
OpenAlexW3012648299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.