Evidence map›Paper›PMID 32235697›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Immunomodulatory Potential of Differently-Terminated Ultra-Small Silicon Carbide Nanoparticles.

Tereza Bělinová, Iva Machová, David Beke, Anna Fučíková, Adam Gali, Zuzana Humlová, Jan Valenta, Marie Hubálek Kalbáčová

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Amino-Termination of Silicon Carbide Nanoparticles.Nanomaterials (Basel, Switzerland) · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tereza BělinováBiomedical Center, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
Iva MachováBiomedical Center, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
David BekeWigner Research Centre for Physics, 1121 Budapest, Hungary.ORCID 0000-0001-6046-8164
Anna FučíkováDepartment of Chemical Physics and Optics, Faculty of Mathematics and Physics, Charles University, 121 16 Prague, Czech Republic.
Adam GaliWigner Research Centre for Physics, 1121 Budapest, Hungary.ORCID 0000-0002-3339-5470
Zuzana HumlováInstitute of Pathological Physiology, 1st Faculty of Medicine, Charles University, 128 53 Prague, Czech Republic.
Jan ValentaDepartment of Chemical Physics and Optics, Faculty of Mathematics and Physics, Charles University, 121 16 Prague, Czech Republic.ORCID 0000-0002-0322-3766
Marie Hubálek KalbáčováBiomedical Center, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.ORCID 0000-0002-3886-2218

Funding

Emberi Eroforrások Minisztériuma NTP-NFTÖ-18-B-0243 national talent programMagyar Tudományos Akadémia János Bolyai ScholarshipMinisterstvo Školství, Mládeže a Tělovýchovy National Sustainability Program I No. LO1503Nemzeti Kutatási Fejlesztési és Innovációs Hivatal EU QuantERA Nanospin project (NKFIH Grant No. 127902)Nemzeti Kutatási Fejlesztési és Innovációs Hivatal National Quantum Technology Project (NKFIH Grant No. 2017-1.2.1-NKP-2017-00001)Nemzeti Kutatási Fejlesztési és Innovációs Hivatal NVKP project (NKFIH Grant No. NVKP_16-1-2016-0043)Nemzeti Kutatási Fejlesztési és Innovációs Hivatal UNKP-19 New National Excellence programUniverzita Karlova v Praze PROGRES Q26Univerzita Karlova v Praze SVV 260390Univerzita Karlova v Praze UNCE/SCI/010
6 · The paper itself

Abstract

Ultra-small nanoparticles with sizes comparable to those of pores in the cellular membrane possess significant potential for application in the field of biomedicine. Silicon carbide ultra-small nanoparticles with varying surface termination were tested for the biological system represented by different human cells (using a human osteoblastic cell line as the reference system and a monocyte/macrophage cell line as immune cells). The three tested nanoparticle surface terminations resulted in the observation of different effects on cell metabolic activity. These effects were mostly noticeable in cases of monocytic cells, where each type of particle caused a completely different response ('as-prepared' particles, i.e., were highly cytotoxic, -OH terminated particles slightly increased the metabolic activity, while -NH

Indexed as

cytotoxicityimmune cellsnanoparticlesosteoblastssilicon carbide

Identifiers

PMID32235697
PMCPMC7153366

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.