Evidence map›Paper›PMID 32235488›Full record

ArticleJournal of clinical medicine2020

Validation of the mTICCS Score as a Useful Tool for the Early Prediction of a Massive Transfusion in Patients with a Traumatic Hemorrhage.

Klemens Horst, Rachel Lentzen, Martin Tonglet, Ümit Mert, Philipp Lichte, Christian D Weber, Philipp Kobbe, Nicole Heussen, Frank Hildebrand

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Observational
  6. mTICCS and its inter-rater reliability to predict the need for massive transfusion in severely injured patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Klemens HorstDepartment of Trauma and Reconstructive Surgery, University Hospital, RWTH 52074 Aachen, Germany.
Rachel LentzenDepartment of Trauma and Reconstructive Surgery, University Hospital, RWTH 52074 Aachen, Germany.
Martin TongletDepartment of Emergency, Liege University Hospital, Domaine du Sart Tilman, 4000 Liege, Belgium.
Ümit MertDepartment of Trauma and Reconstructive Surgery, University Hospital, RWTH 52074 Aachen, Germany.
Philipp LichteDepartment of Trauma and Reconstructive Surgery, University Hospital, RWTH 52074 Aachen, Germany.
Christian D WeberDepartment of Trauma and Reconstructive Surgery, University Hospital, RWTH 52074 Aachen, Germany.
Philipp KobbeDepartment of Trauma and Reconstructive Surgery, University Hospital, RWTH 52074 Aachen, Germany.
Nicole HeussenDepartment of Medical Statistics, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-6134-7206
Frank HildebrandDepartment of Trauma and Reconstructive Surgery, University Hospital, RWTH 52074 Aachen, Germany.
RWTH Aachen University · DESigmund Freud Privatuniversität Wien · ATUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The modified Trauma-Induced Coagulopathy Clinical Score (mTICCS) presents a new scoring system for the early detection of the need for a massive transfusion (MT). While validated in a large trauma cohort, the comparison of mTICCS to established scoring systems is missing. This study therefore validated the ability of six scoring systems to stratify patients at risk for an MT at an early stage after trauma. A dataset of severely injured patients (ISS ≥ 16) derived from the database of a level I trauma center (2010-2015) was used. Scoring systems assessed were Trauma-Associated Severe Hemorrhage (TASH) score, Prince of Wales Hospital (PWH) score, Larson score, Assessment of Blood Consumption (ABC) score, Emergency Transfusion Score (ETS), and mTICCS. Demographics, diagnostic data, mechanism of injury, injury pattern (graded by AIS), and outcome (length of stay, mortality) were analyzed. Scores were calculated, and the area under the receiver operating characteristic curves (AUCs) were evaluated. From the AUCs, the cut-off point with the best relationship of sensitivity-to-specificity was used to recalculate sensitivity, specificity, positive predictive values (PPV), and negative predictive values (NPV). A total of 479 patients were included; of those, blunt trauma occurred in 92.3% of patients. The mean age of patients was 49 ± 22 years with a mean ISS of 25 ± 29. The overall MT rate was 8.4% (

Indexed as

bleedingmassive transfusionmTICCSmultiple traumapolytraumashockTICCStransfusion

Identifiers

PMID32235488
PMCPMC7230969
OpenAlexW3013268191

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.