Evidence map›Paper›PMID 32235377›Full record

ArticleMicroorganisms2020

Characterization of the Duodenal Mucosal Microbiome in Obese Adult Subjects by 16S rRNA Sequencing.

Carmela Nardelli, Ilaria Granata, Valeria D'Argenio, Salvatore Tramontano, Debora Compare, Mario Rosario Guarracino, Gerardo Nardone, Vincenzo Pilone, Lucia Sacchetti

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Diet, adiposity, and the gut microbiota from infancy to adolescence: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Duodenal microbiota profiling and its effects on gastrointestinal tract dysfunction.Frontiers in cellular and infection microbiology · 2026
    Article
  6. Article
  7. Review
  8. A novel method for precise endoscopic sampling of duodenal microbiota.Frontiers in cellular and infection microbiology · 2025
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  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Carmela NardelliDepartment of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-9540-3405
Ilaria GranataInstitute for High Performance Computing and Networking (ICAR), National Research Council (CNR), 80131 Naples, Italy.
Valeria D'ArgenioCEINGE Biotecnologie Avanzate S. C. a R. L., 80131 Naples, Italy.ORCID 0000-0001-9273-3698
Salvatore TramontanoDepartment of Medicine and Surgery, University of Salerno, 84084 Salerno, Italy.
Debora CompareDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.
Mario Rosario GuarracinoInstitute for High Performance Computing and Networking (ICAR), National Research Council (CNR), 80131 Naples, Italy.
Gerardo NardoneDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.
Vincenzo PiloneDepartment of Medicine and Surgery, University of Salerno, 84084 Salerno, Italy.
Lucia SacchettiCEINGE Biotecnologie Avanzate S. C. a R. L., 80131 Naples, Italy.
Ceinge Biotecnologie Avanzate (Italy) · ITUniversity of Naples Federico II · ITUniversity of Salerno · ITInstitute for High Performance Computing and Networking · ITUniversità degli studi di Cassino e del Lazio Meridionale · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota may have an impact on obesity. To date, the majority of studies in obese patients reported microbiota composition in stool samples. The aim of this study was to investigate the duodenal mucosa dysbiosis in adult obese individuals from Campania, a region in Italy with a very high percentage of obese people, to highlight microbial taxa likely associated with obesity. Duodenum biopsies were taken during upper gastrointestinal endoscopy in 19 obese (OB) and 16 lean control subjects (CO) and microbiome studied by 16S rRNA gene sequencing. Duodenal microbiome in our groups consisted of six phyla: Proteobacteria, Firmicutes, Actinobacteria, Fusobacteria, Bacteroidetes and Acidobacteria. Proteobacteria (51.1% vs. 40.1%) and Firmicutes (33.6% vs. 44.9%) were significantly (

Indexed as

duodenummicrobiomeobesity

Identifiers

PMID32235377
PMCPMC7232320
OpenAlexW3013436833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.