Evidence map›Paper›PMID 32235357›Full record

ArticleInternational journal of molecular sciences2020

Fluoride Affects Dopamine Metabolism and Causes Changes in the Expression of Dopamine Receptors (D1R and D2R) in Chosen Brain Structures of Morphine-Dependent Rats.

Patrycja Kupnicka, Joanna Listos, Maciej Tarnowski, Agnieszka Kolasa-Wołosiuk, Agnieszka Wąsik, Agnieszka Łukomska, Katarzyna Barczak, Izabela Gutowska, Dariusz Chlubek, Irena Baranowska-Bosiacka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Patrycja KupnickaDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0002-0756-6483
Joanna ListosDepartment of Pharmacology and Pharmacodynamics, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland.
Maciej TarnowskiDepartment of Physiology, Pomeranian Medical University, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0002-3869-5077
Agnieszka Kolasa-WołosiukDepartment of Histology and Embryology, Pomeranian Medical University, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0002-6933-7643
Agnieszka WąsikMaj Institute of Pharmacology PAS, Department of Neurochemistry, 12 Smętna Street, 31-343 Krakow, Poland.
Agnieszka ŁukomskaDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0002-2243-6775
Katarzyna BarczakDepartment of Conservative Dentistry and Endodontics, Powstańców Wlkp. 72 St., Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.ORCID 0000-0001-6381-566X
Izabela GutowskaDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0001-8823-0473
Dariusz ChlubekDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0003-4497-4395
Irena Baranowska-BosiackaDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.ORCID 0000-0001-9187-8895
Pomeranian Medical University · PLMaj Institute of Pharmacology · PLMedical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disturbances caused by excess or shortages of certain elements can affect the cerebral reward system and may therefore modulate the processes associated with the development of dependence as was confirmed by behavioural studies on animals addicted to morphine. Earlier publications demonstrated and proved the neurodegenerative properties of both low and high doses of fluoride ions in animal experiments and in epidemiological and clinical studies. The aim of the experiments conducted in the course of the present study was to analyse the effect of pre- and postnatal exposure to 50 ppm F

Indexed as

AnimalsBehavior, AnimalBrainCerebellumCorpus StriatumDopamineFemaleFluoridesGene Expression RegulationHippocampusMaternal ExposureMetabolic Networks and PathwaysModels, AnimalMorphinePrefrontal CortexRatsDopamineFluoridesMorphineReceptors, Dopamine D1Receptors, Dopamine D2dependencedopaminedopamine receptorsfluoridemorphine

Identifiers

PMID32235357
PMCPMC7177607
OpenAlexW3013644172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.