Evidence map›Paper›PMID 32235273›Full record

ReviewCurrent opinion in nephrology and hypertension2020

Applications of machine learning methods in kidney disease: hope or hype?

Lili Chan, Akhil Vaid, Girish N Nadkarni

Abstract readReview
In one paragraph

Review in Current opinion in nephrology and hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Geometric Deep Learning for Multimodal Data in CKD.Journal of the American Society of Nephrology : JASN · 2025
    Article
  5. Article
  6. Article
  7. Prediction of Mortality and Major Adverse Kidney Events in Critically Ill Patients With Acute Kidney Injury.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lili ChanDivision of Nephrology, Department of Medicine The Charles Bronfman Institute of Personalized Medicine The Hasso Plattner Institute for Digital Health The BioMe Phenomics Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Akhil Vaid
Girish N Nadkarni

Funding

Incorporating genomics into the clinical care of diverse NYC childrenU01HG009610 · NHGRI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GELB, BRUCE D, HOROWITZ, CAROL R · 2017 to 2021
$17.0M
Multi-Omics and Chronic Kidney Disease: Correlation with HistologyR01DK108803 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Morgan Erika Grams, EUGENE P. RHEE · 2016 to 2026
$6.4M
Genomic Medicine Pilot For Hypertension And Kidney Disease In Primary CareU01HG007278 · NHGRI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HOROWITZ, CAROL R · 2013 to 2018
$5.7M
Elucidating Genetic and Environmental Second Hits in Racial and Ethnic Minorities with APOL1 High-Risk GenotypesR01DK127139 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NADKARNI, GIRISH NITIN · 2021 to 2025
$4.0M
Artificial Intelligence to Predict Outcomes in Patients with Acute Kidney Injury on Continuous Renal Replacement TherapyR01DK133539 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Girish Nitin Nadkarni, Javier A. Neyra · 2023 to 2026
$2.6M
North East Consortium for Transplant outcomes in APOL1 kidney Recipients (NECTAR) Clinical CenterU01DK116100 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI Darshana Dadhania, Samira Farouk · 2017 to 2026
$2.5M
Risk Clustering and Stratification in Genetically High-Risk Individuals Using Electronic Medical Records and BiomarkersK23DK107908 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NADKARNI, GIRISH NITIN · 2016 to 2020
$930k
Artificial Intelligence to Predict Outcomes in Patients with Acute Kidney Injury on Continuous Renal Replacement TherapyR56DK126930 · NIDDK · UNIVERSITY OF KENTUCKY · PI NADKARNI, GIRISH NITIN, NEYRA, JAVIER A. · 2020 to 2020
$100k
NHGRI NIH HHS U01 HG007278NHGRI NIH HHS U01 HG009610NIDDK NIH HHS K23 DK107908NIDDK NIH HHS R01 DK108803NIDDK NIH HHS R01 DK127139NIDDK NIH HHS R01 DK133539NIDDK NIH HHS R56 DK126930NIDDK NIH HHS U01 DK116100
6 · The paper itself

Abstract

purpose of reviewThe universal adoption of electronic health records, improvement in technology, and the availability of continuous monitoring has generated large quantities of healthcare data. Machine learning is increasingly adopted by nephrology researchers to analyze this data in order to improve the care of their patients. RECENT

findingsIn this review, we provide a broad overview of the different types of machine learning algorithms currently available and how researchers have applied these methods in nephrology research. Current applications have included prediction of acute kidney injury and chronic kidney disease along with progression of kidney disease. Researchers have demonstrated the ability of machine learning to read kidney biopsy samples, identify patient outcomes from unstructured data, and identify subtypes in complex diseases. We end with a discussion on the ethics and potential pitfalls of machine learning. SUMMARY: Machine learning provides researchers with the ability to analyze data that were previously inaccessible. While still burgeoning, several studies show promising results, which will enable researchers to perform larger scale studies and clinicians the ability to provide more personalized care. However, we must ensure that implementation aids providers and does not lead to harm to patients.

Indexed as

Machine LearningAlgorithmsHumansKidney DiseasesNatural Language ProcessingTranslational Research, Biomedical

Identifiers

PMID32235273
PMCPMC7770625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.