Evidence map›Paper›PMID 32235031›Full record

ArticleJournal of neurogastroenterology and motility2020

Measurement of Esophageal Nocturnal Baseline Impedance: A Simplified Method.

Yoshimasa Hoshikawa, Akinari Sawada, Shirley Sonmez, Kornilia Nikaki, Philip Woodland, Etsuro Yazaki, Daniel Sifrim

Open access · diamondAbstract read
In one paragraph

Article in Journal of neurogastroenterology and motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
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  4. Reflux Testing: Wireless pH, Impedance-pH, and Mucosal Impedance.Gastrointestinal endoscopy clinics of North America · 2025
    Review
  5. Observational
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  20. Complex Gastroesophageal Reflux Disease.Gastro hep advances · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yoshimasa HoshikawaBarts and the London School of Medicine and Dentistry, Queen Mary University of London.ORCID https://orcid.org/0000-0003-3031-0993
Akinari SawadaBarts and the London School of Medicine and Dentistry, Queen Mary University of London.
Shirley SonmezBarts and the London School of Medicine and Dentistry, Queen Mary University of London.
Kornilia NikakiBarts and the London School of Medicine and Dentistry, Queen Mary University of London.
Philip WoodlandBarts and the London School of Medicine and Dentistry, Queen Mary University of London.
Etsuro YazakiBarts and the London School of Medicine and Dentistry, Queen Mary University of London.
Daniel SifrimBarts and the London School of Medicine and Dentistry, Queen Mary University of London.ORCID https://orcid.org/0000-0002-4894-0523
Queen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsMean nocturnal baseline impedance (MNBI) during multichannel intraluminal impedance pH-monitoring (MII-pH) reflects the status of esophageal mucosal integrity. MNBI is suggested as an adjunctive method to distinguish patients with true gastroesophageal reflux disease (GERD) from functional heartburn (FH) and might predict outcomes for anti-reflux treatment. However, current methodology for calculation of MNBI is time-consuming and subject to operator-dependent selection bias. We aim to simplify and provide a more objective method to calculate MNBI.

methodsWe retrospectively analyzed 100 MII-pH tracings from 20 patients with erosive reflux disease, 20 with non-erosive reflux disease (NERD), 20 with reflux hypersensitivity, 20 with functional heartburn (FH), and 20 healthy asymptomatic volunteers. We compared the current "conventional" MNBI analysis with our "simple" MNBI analysis measured by selecting the whole supine period using the impedance average calculation function in the MII-pH software.

resultsAbsolute values were very similar and there was a strong correlation between conventional and simple MNBI values in the most distal channel in all groups (

conclusionSimple MNBI analysis provides very similar values and has an excellent correlation with conventional MNBI analysis.

Indexed as

Electric impedanceEsophageal mucosaEsophagitisGastroesophageal refluxHeartburn

Identifiers

PMID32235031
PMCPMC7176501
OpenAlexW3014805000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.