ArticleiScience2020
Self-Enhanced Carbonized Polymer Dots for Selective Visualization of Lysosomes and Real-Time Apoptosis Monitoring.
Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 34 citations in OpenAlex.
- Carbon dots as probes in FLIM:a review of applications and advances in cellular imaging.RSC advances · 2025Review
- Optimization of Preparation Technology for PET-Based Carbon Dots by Response Surface Method and Its Application.Journal of fluorescence · 2025Article
- Green synthesis and multifaceted applications: challenges and innovations in carbon dot nanocomposites.Discover nano · 2024Review
- Semiconducting polymer dots for multifunctional integrated nanomedicine carriers.Materials today. Bio · 2024Review
- Synthesis and Characterization of Amorphous Lawsone Polymer Dots for Fluorescent Applications.ACS applied nano materials · 2023Article
- The Preparation of Golgi Apparatus-Targeted Polymer Dots Encapsulated with Carbon Nanodots of Bright Near-Infrared Fluorescence for Long-Term Bioimaging.Molecules (Basel, Switzerland) · 2023Article
- Electron-phonon coupling-assisted universal red luminescence of o-phenylenediamine-based carbon dots.Light, science & applications · 2022Article
- Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review.Small science · 2022Article
- A Versatile Pep-CPDs Nanoprobe for Rapid Detection of mTBI Biomarker in Clinical Instances and Safe Fluorescence ImagingFrontiers in bioengineering and biotechnology · 2022Article
- Simple and Green Synthesis of Carbonized Polymer dots from Nylon 66 Waste Fibers and its Potential Application.ACS omega · 2021Article
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protons are highly related to cell viability during physiological and pathological processes. Developing new probes to monitor the pH variation could be extremely helpful to understand the viability of cells and the cell death study. Carbonized polymer dots (CPDs) are superior biocompatible and have been widely applied in bioimaging field. Herein, a new type of extreme-pH suitable CPDs was prepared from citric acid and o-phenylenediamine (CA/oPD-CPDs). Due to the co-existence of hydrophilic and hydrophobic groups, CA/oPD-CPDs tend to aggregate in neutral condition with a dramatic decrease of fluorescence, but disperse well in both acidic and alkaline conditions with brighter emission. This specialty enables them to selectively illuminate lysosomes in cells. Moreover, CA/oPD-CPDs in the cytoplasm could serve as a sustained probe to record intracellular pH variation during apoptosis. Furthermore, CA/oPD-CPDs present a continuous fluorescence increase upon 2-h laser irradiation in living cells, underscoring this imaging system for long-term biological recording.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.