Evidence map›Paper›PMID 32234250›Full record

Observational studyBritish journal of anaesthesia2020

Spinal anaesthesia for patients with coronavirus disease 2019 and possible transmission rates in anaesthetists: retrospective, single-centre, observational cohort study.

Qi Zhong, Yin Y Liu, Qiong Luo, Yu F Zou, Hai X Jiang, Hui Li, Jing J Zhang, Zhen Li, Xin Yang, Min Ma and 5 more

Erratum issued Registry-linked trialOpen access · bronzeAbstract readObservational Study
In one paragraph

Observational study in British journal of anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04392323 (Incidence of COVID-19 Test Conversion in Post-surgical Patients), which is not on this map. Cited by 63 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 5 pooled it
3.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04392323 nacompletednot on this map

Incidence of COVID-19 Test Conversion in Post-surgical Patients

TypeinterventionalSponsorNorthwell HealthRan2020 to 2020Enrolled111ConditionsSars-CoV2ArmsCOVID-19 PCR and Serology
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 5 syntheses or guidelines pooled it, 123 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
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  5. Guidelines: Anaesthesia in the context of COVID-19 pandemic.Anaesthesia, critical care & pain medicine · 2020
    Guideline
  6. Article
  7. Review
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  11. Article
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  18. Anesthesia in the times of COVID-19.Journal of anesthesia · 2021
    Article
  19. COVID-19 transmission: a rapid systematic review of current knowledge.Osong public health and research perspectives · 2021
    Article
  20. Observational

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Qi ZhongDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Yin Y LiuDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Qiong LuoDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Yu F ZouDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Hai X JiangDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Hui LiDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Jing J ZhangDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Zhen LiDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Xin YangDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Min MaDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Li J TangDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.
Ying Y ChenDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China. Electronic address: chenyingy@whu.edu.cn.
Feng ZhengDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China. Electronic address: fengzheng@whu.edu.cn.
Jian J KeDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China. Electronic address: 1219628972@qq.com.
Zong Z ZhangDepartment of Anaesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China. Electronic address: zhangzz@whu.edu.cn.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe safety of performing spinal anaesthesia for both patients and anaesthetists alike in the presence of active infection with the novel coronavirus disease 2019 (COVID-19) is unclear. Here, we report the clinical characteristics and outcomes for both patients with COVID-19 and the anaesthetists who provided their spinal anaesthesia.

methodsForty-nine patients with radiologically confirmed COVID-19 for Caesarean section or lower-limb surgery undergoing spinal anaesthesia in Zhongnan Hospital, Wuhan, China participated in this retrospective study. Clinical characteristics and perioperative outcomes were recorded. For anaesthesiologists exposed to patients with COVID-19 by providing spinal anaesthesia, the level of personal protective equipment (PPE) used, clinical outcomes (pulmonary CT scans), and confirmed COVID-19 transmission rates (polymerase chain reaction [PCR]) were reviewed.

resultsForty-nine patients with COVID-19 requiring supplementary oxygen before surgery had spinal anaesthesia (ropivacaine 0.75%), chiefly for Caesarean section (45/49 [91%]). Spinal anaesthesia was not associated with cardiorespiratory compromise intraoperatively. No patients subsequently developed severe pneumonia. Of 44 anaesthetists, 37 (84.1%) provided spinal anaesthesia using Level 3 PPE. Coronavirus disease 2019 infection was subsequently confirmed by PCR in 5/44 (11.4%) anaesthetists. One (2.7%) of 37 anaesthetists who wore Level 3 PPE developed PCR-confirmed COVID-19 compared with 4/7 (57.1%) anaesthetists who had Level 1 protection in the operating theatre (relative risk reduction: 95.3% [95% confidence intervals: 63.7-99.4]; P<0.01).

conclusionsSpinal anaesthesia was delivered safely in patients with active COVID-19 infection, the majority of whom had Caesarean sections. Level 3 PPE appears to reduce the risk of transmission to anaesthetists who are exposed to mildly symptomatic surgical patients.

Indexed as

AnesthetistsAdultAnesthesia, SpinalAnesthesiologistsBetacoronavirusChinaCoronavirus InfectionsCOVID-19FemaleHumansMalePandemicsPersonal Protective EquipmentPneumonia, ViralRetrospective StudiesRiskCOVID-19perioperative clinical characteristicsspinal anaesthesiasurgery

Identifiers

PMID32234250
PMCPMC7270271
OpenAlexW3013242875

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.