Observational studyBMC musculoskeletal disorders2020
Obesity-associated poor muscle quality: prevalence and association with age, sex, and body mass index.
Observational study in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Muscle strength, muscle morphology, and oxidative capacity in normal weight versus overweight and obese youth: a systematic review with meta-analysis.Scientific reports · 2025Pooled it
- Body composition changes during weight reduction with tirzepatide in the SURMOUNT-1 study of adults with obesity or overweight.Diabetes, obesity & metabolism · 2025Trial
- Impact of a Multicomponent Exercise Training Program on Muscle Strength After Bariatric Surgery: A Randomized Controlled Trial.Obesity surgery · 2024Trial
- Impact of obesity and type 2 diabetes on muscle power, quality, and force-velocity, and their relation to functional capacity.Journal of diabetes and metabolic disorders · 2026Article
- Rethinking Biva in obesity: systematic vector displacement across the adiposity spectrum.European journal of clinical nutrition · 2026Article
- The Effects of Social Dance on Muscular Fitness and Longevity-Related Circulating Biomarkers in the Elderly.Journal of functional morphology and kinesiology · 2026Article
- Influence of Obesity and IL-6 on Human Postprandial Amino Acid and Protein Metabolism at Whole-body and Tissue Level.The Journal of clinical endocrinology and metabolism · 2026Article
- Effect of Tofogliflozin on Skeletal Muscle Mitochondrial Function in Male Diabetic Mice With Muscle Atrophy.Journal of the Endocrine Society · 2026Article
- Association between muscle quality index and time to stand up from the prone position in community-dwelling older adults.PloS one · 2026Article
- Passiflora edulis f. flavicarpa Extract Prevents Muscle Atrophy and Insulin Resistance in High-Fat Diet-Induced Obese Rats via Regulating the Nrf2, NF-κB, and IRS-1/PI3K/AKT Signaling Pathways.Oxidative medicine and cellular longevity · 2026Article
- Gingival bleeding and lower number of natural teeth are predictive factors of low muscle strength in obese adults: a cross-sectional study.Frontiers in oral health · 2026Article
- Association of Healthy Eating Index-2020 with muscle mass among the middle-aged individuals - a cross-sectional study based on NHANES from 2011 to 2018.Nutrition journal · 2025Article
- Associations between muscle quality index and cardiac function in older adults with sarcopenia and obesity.Aging clinical and experimental research · 2025Article
- Are we giving too much weight to lean mass loss?Molecular metabolism · 2025Review
- Muscle quality decline and fat infiltration in non-elderly OSA patients: associations with metabolic abnormalities.Journal of translational medicine · 2025Article
- Poor muscle quality: A hidden and detrimental health condition in obesity.Reviews in endocrine & metabolic disorders · 2025Review
- Compared to total serum testosterone, calculated free testosterone has a stronger association with lean mass, muscle strength, power, and physical function in older men.Aging clinical and experimental research · 2025Article
- Sarcopenic obesity: a review.Archives of endocrinology and metabolism · 2025Review
- Association Between Euthyroidism and Muscular Parameters in Adults with an Excess of Fat Mass: A Preliminary Study.Healthcare (Basel, Switzerland) · 2025Article
- Diabetes and smoking are associated with dynapenic abdominal obesity in patients with chronic kidney disease: a cross-sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundMuscle quality (i.e., the expression of muscle function per unit of muscle mass) has been proposed as a clinically-relevant measure to detect individuals at risk of functional incapacity. Individuals with obesity might be at an increased risk of having poor muscle quality. Thus, we aimed to analyze the prevalence of poor muscle quality in obese individuals, to determine associated variables, and to provide normative values for this population.
methods203 individuals with obesity (103 women, age: 18-75 years, body mass index (BMI): 35-64 kg·m
resultsAge and being a woman were inversely associated with specific muscle strength, with age being also inversely associated with specific muscle power. A small proportion of participants (6%) presented with an impaired (i.e., low/poor) specific muscle power while most of them (96%) had impaired specific muscle strength. Eventually, 84% of the participants were deemed to have poor muscle quality. Being a woman (odds ratio [OR]: 18.09, 95% confidence intervals [CI]: 4.07-80.38), age (OR: 1.06, 95%CI: 1.03-1.10) and BMI (OR: 1.22, 95%CI: 1.07-1.38) were independently associated with a higher risk of poor muscle quality in adjusted analyses.
conclusionsThese findings show a high prevalence of poor muscle quality among individuals with obesity, with age, sex and BMI being independent predictors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.