Evidence map›Paper›PMID 32233984›Full record

ArticleCell cycle (Georgetown, Tex.)2020

miR-552 promotes laryngocarcinoma cells proliferation and metastasis by targeting p53 pathway.

Jia Gu, Tao Han, Lei Sun, Ai-Hui Yan, Xue-Jun Jiang

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Non-coding RNA and drug resistance in head and neck cancer.Cancer drug resistance (Alhambra, Calif.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jia GuDepartment of Otolaryngology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Tao HanDepartment of Oncology, The General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
Lei SunDepartment of Thoracic Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.ORCID 0000-0002-0264-8148
Ai-Hui YanDepartment of Otolaryngology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Xue-Jun JiangDepartment of Otolaryngology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
First Hospital of China Medical University · CNGeneral Hospital of Shenyang Military Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous researches show that MicroRNAs (miRNAs) participate in tumorigenesis, progression, recurrence and drug resistance of malignant tumors, including laryngocarcinoma. miR-552 works as an oncogene in both colorectal cancer and liver cancer. However, the potential role of miR-552 in laryngocarcinoma is unknown. Herein, we for first found that miR-552 expression was upregulated in laryngocarcinoma tissues compared with their normal controls. Moreover, miR-552 expression was also increasing in the laryngocarcinoma cells. miR-552 interference inhibited the proliferation and metastasis of laryngocarcinoma cells

Indexed as

AnimalsCase-Control StudiesCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansLaryngeal NeoplasmsLiver NeoplasmsMaleMiceMice, NudeMicroRNAsNeoplasm InvasivenessSignal TransductionTransfectionMicroRNAsMIRN552 microRNA, humanTP53 protein, humanTumor Suppressor Protein p53LaryngocarcinomametastasismiR-552p53proliferation

Identifiers

PMID32233984
PMCPMC7217371
OpenAlexW3014699139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.