Evidence map›Paper›PMID 32233736›Full record

ArticleSLAS discovery : advancing life sciences R & D2020

Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences.

Jacob S Roth, Tobie D Lee, Dorian M Cheff, Maya L Gosztyla, Rosita R Asawa, Carina Danchik, Sam Michael, Anton Simeonov, Carleen Klumpp-Thomas, Kelli M Wilson and 1 more

Abstract read
In one paragraph

Article in SLAS discovery : advancing life sciences R & D, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Cell Adhesion-Based Reconstitution Method for Studying Cell Polarity.Frontiers in cell and developmental biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jacob S RothNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Tobie D LeeNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Dorian M CheffNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Maya L GosztylaNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.ORCID 0000-0003-4758-4800
Rosita R AsawaNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Carina DanchikNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Sam MichaelNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Anton SimeonovNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Carleen Klumpp-ThomasNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Kelli M WilsonNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Matthew D HallNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.ORCID 0000-0002-5073-442X

Funding

Research Services Section (RSS)ZICTR000242 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI WILSON, KELLI · 2015 to 2025
$64.9M
Helping to End Addiction Long-term (HEAL): Probe/Drug Lead ProductionZIATR000346 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI HALL, MATTHEW · 2018 to 2023
$14.9M
Intramural NIH HHS ZIA TR000346
6 · The paper itself

Abstract

Quality control monitoring of cell lines utilized in biomedical research is of utmost importance and is critical for the reproducibility of data. Two key pitfalls in tissue culture are 1) cell line authenticity and 2)

Indexed as

Quality ControlCell Culture TechniquesCell Line, TumorHumansMicrosatellite RepeatsMycoplasmaNational Center for Advancing Translational Sciences (U.S.)Polymerase Chain ReactionTranslational Research, BiomedicalUnited Statescell culturecontaminationMycoplasmaquality controlreproducibility

Identifiers

PMID32233736
PMCPMC8506661

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.