Evidence map›Paper›PMID 32233608›Full record

ArticleMathematical biosciences and engineering : MBE2019

Pulsatile flow through idealized renal tubules: Fluid-structure interaction and dynamic pathologies.

Niksa Praljak, Shawn D Ryan, Andrew Resnick

Abstract read
In one paragraph

Article in Mathematical biosciences and engineering : MBE, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Niksa PraljakDepartment of Mathematics and Statistics, Cleveland State University, Cleveland OH 44115, USA.
Shawn D RyanDepartment of Mathematics and Statistics, Cleveland State University, Cleveland OH 44115, USA.
Andrew ResnickDepartment of Physics, Cleveland State University, Cleveland OH 44115, USA.

Funding

Bending Primary Cilia: evidence for a structure-function relationship?R15GM132829 · NIGMS · CLEVELAND STATE UNIVERSITY · PI RESNICK, ANDREW · 2019 to 2019
$445k
NIGMS NIH HHS R15 GM132829
6 · The paper itself

Abstract

Kidney tubules are lined with flow-sensing structures, yet information about the flow itself is not easily obtained. We aim to generate a multiscale biomechanical model for analyzing fluid flow and fluid-structure interactions within an elastic kidney tubule when the driving pressure is pulsatile. We developed a two-dimensional macroscopic mathematical model of a single fluid-filled tubule corresponding to a distal nephron segment and determined both flow dynamics and wall strains over a range of driving frequencies and wall compliances using finite-element analysis. The results presented here demonstrate good agreement with available analytical solutions and form a foundation for future inclusion of elastohydrodynamic coupling by neighboring tubules. Overall, we are interested in exploring the idea of

Indexed as

Kidney TubulesModels, TheoreticalFinite Element AnalysisPulsatile Flowfluid-structure interactionskidneymodelingphysiologypulsatile flow

Identifiers

PMID32233608
PMCPMC8533031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.