ReviewTurkish journal of medical sciences2020
Thiol-disulfide homeostasis: an integrated approach with biochemical and clinical aspects
Review in Turkish journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Utility of thiol/disulphide homeostasis as a biomarker for acute appendicitis: a systematic review and meta-analysis.Pediatric surgery international · 2024Pooled it
- Meta-analysis of changes in thiol-disulfide homeostasis during preeclampsia.Biomolecules & biomedicine · 2024Pooled it
- The effects of dexmedetomidine on thiol/disulphide homeostasis in coronary artery bypass surgery: a randomized controlled trial.BMC anesthesiology · 2024Trial
- Oxidative Stress During ERCP: Biomarker or Bystander?Digestive diseases and sciences · 2026Article
- Thiol-Disulfide Homeostasis and Erythrocyte Glutathione Balance in ST-Elevation Myocardial Infarction: A Prospective Case-Control Study.Journal of cardiovascular development and disease · 2026Article
- Serum Molecular Fingerprints of Oxidative Stress Underlying Neurocognitive and Motor Dysfunction in Pesticide-Exposed Populations.The European journal of neuroscience · 2026Article
- Altered Thiol-Disulfide Homeostasis in Sarcoidosis: A Case-Control Study.Medicina (Kaunas, Lithuania) · 2026Article
- Thiol-disulfide homeostasis in ovarian cancer: comparative analysis with benign neoplasia and healthy women.Turkish journal of obstetrics and gynecology · 2026Article
- Observational
- Oxidative Stress in Asthma Pathogenesis: Mechanistic Insights and Emerging Biomarker Signatures.International journal of molecular sciences · 2026Review
- Effects of different preoxygenation strategies on dynamic thiol-disulfide homeostasis and blood gas parameters in patients undergoing laparoscopic cholecystectomy.Perioperative medicine (London, England) · 2026Article
- Altered serum biomarkers of oxidative stress and antioxidant capacity in primary open-angle glaucoma.Scientific reports · 2026Article
- Thiol/Disulfide Homeostasis in Lung Cancer: Insights from a Clinical Study.Antioxidants (Basel, Switzerland) · 2026Article
- Protein oxidation, glycation, and carbamylation in patients with adrenal masses.Frontiers in molecular biosciences · 2026Article
- Association of the children's dietary inflammatory index (c-DII) with thiol/disulfide homeostasis in pediatric glycogen storage disease: a cross-sectional exploratory study.Frontiers in nutrition · 2026Article
- Oxidative Stress, Glutathione System Activity, and Zinc/Selenium Imbalance in Adult Measles of Varying Severity According to Vaccination Status.Infection and drug resistance · 2026Article
- Contribution of adenosine ATurkish journal of medical sciences · 2026Article
- Thiol-disulfide parameters in recurrent aphthous stomatitis: A cross-sectional study.BMC oral health · 2025Article
- Article
- Thiol/Disulfide Homeostasis as a New Oxidative Stress Marker in Patients with COPD.Diagnostics (Basel, Switzerland) · 2025Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dynamic thiol-disulfide homeostasis (TDH) is a new area has begun to attract more scrutiny. Dynamic TDH is reversal of thiol oxidation in proteins and represents the status of thiols (-SH) and disulfides (-S-S-). Organic compounds containing the sulfhydryl group is called thiol, composed of sulfur and hydrogen atoms. Disulfides are the most important class of dynamic, redox responsive covalent bonds build in between two thiol groups. For many years, thiol levels were analyzed by several methods. During last years, measurements of disulfide levels have been analyzed by a novel automated method, developed by Erel and Neselioglu. In this method, addition to thiol (termed as native thiol) levels, disulfide levels were also measured and sum of native thiol and disulfide levels were termed as total thiol. Therefore, TDH was begun to be understood in organism. In healthy humans, TDH is maintained within a certain range. Dysregulated dynamic TDH has been implicated several disorders with unknown etiology. A growing body of evidence has demonstrated that the thiol-disulfide homeostasis is involved in variety diseases, such as diabetes mellitus, hypertension, nonsmall cell lung cancer, familial Mediterranean fever (FMF), inflammatory bowel diseases, occupational diseases, gestational diabetes mellitus and preeclampsia. These results may elucidate some pathogenic mechanism or may be a predictor indicating diagnostic clue, prognostic marker or therapeutic sign. In conclusion, protection of the thiol-disulfide homeostasis is of great importance for the human being. Evidence achieved so far has proposed that thiol-disulfide homeostasis is an important issue needs to elucidate wholly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.