ArticleAddiction (Abingdon, England)2020
A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study.
Article in Addiction (Abingdon, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
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- Lockdown influence on diet and physical activity of seniors; has it weight consequences?Central European journal of public health · 2024Article
- ALT levels, alcohol use, and metabolic risk factors have prognostic relevance for liver-related outcomes in the general population.JHEP reports : innovation in hepatology · 2024Article
- Perceived Risk of Binge Drinking among Older Alcohol Users: Associations with Alcohol Use Frequency, Binge Drinking, Alcohol Use Disorder, and Alcohol Treatment Use.International journal of environmental research and public health · 2024Article
- Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in The Collaborative Study on the Genetics of Alcoholism.Alcohol, clinical & experimental research · 2023Article
- Past-month binge drinking and cannabis use among middle-aged and older adults in the United States, 2015-2019.Alcohol (Fayetteville, N.Y.) · 2023Article
- Alcohol Use and Blood Pressure Among Adults with Hypertension: the Mediating Roles of Health Behaviors.Journal of general internal medicine · 2022Article
- Risk Factors and Cardiovascular Disease in the Elderly.Reviews in cardiovascular medicine · 2022Review
- Social connectedness and dementia prevention: Pilot of the APPLE-Tree video-call intervention during the Covid-19 pandemic.Dementia (London, England) · 2021Article
- Endorsement of specific alcohol use disorder criterion items changes with age in individuals with persistent alcohol use disorders in 2 generations of the San Diego Prospective Study.Alcoholism, clinical and experimental research · 2021Article
- Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder.Brain sciences · 2021Article
- Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder.Brain sciences · 2021Article
- A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study.Addiction (Abingdon, England) · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
aimsTo investigate associations of life-time hazardous and binge drinking with biomarkers of cardiometabolic health, liver function, cardiovascular disease (CVD) and mortality.
designProspective cohort study with median follow-up time to CVD incidence of 4.5 years.
settingLondon, UK: civil servants within the Whitehall II Study.
participantsA total of 4820 drinkers aged 59-83 years with biological measurements during the 2011-12 survey. MEASUREMENTS: Hazardous drinking was defined as having an AUDIT-C score ≥ 5 calculated at each decade of life, forming the following groups: never hazardous drinker, former early (stopping before age 50), former later (stopping after age 50), current hazardous drinker and consistent hazardous drinker (hazardous drinker at each decade of life).
findingsMore than half the sample had been hazardous drinkers at some point during their life-time, comprising former early (< age 50) (19%), former later (≥ age 50) (11%), current (21%) and consistent hazardous drinker (AUDIT-C ≥ 5 across life (5%). After adjusting for covariates, waist circumference was larger with more persistent hazardous drinking (e.g. compared with never hazardous drinkers, former early had increased waist circumference by 1.17 cm [95% confidence interval (CI) = 0.25-2.08]; former later by 1.88 cm (CI = 0.77-2.98); current by 2.44 cm (CI = 1.50-3.34) and consistent hazardous drinker by 3.85 cm (CI = 2.23-5.47). Current hazardous drinkers had higher systolic blood pressure (2.44 mmHg, CI = 1.19-3.68) and fatty liver index scores (4.05 mmHg, CI = 2.92-5.18) than never hazardous drinkers. Current hazardous drinkers [hazard ratio (HR) = 2.75, CI = 1.44-5.22) had an elevated risk of stroke, and former later hazardous drinkers had an elevated risk of non-CVD mortality (HR = 1.93, CI = 1.19-3.14) than never hazardous drinkers. Life-time binge drinking was associated with larger waist circumferences and poorer liver function compared with never binge drinkers.
conclusionHazardous drinking may increase cardiometabolic risk factors; this is made worse by persistent hazardous drinking throughout life, particularly in relation to weight gain, suggesting benefits of early intervention.
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