Evidence map›Paper›PMID 32232647›Full record

ArticleJapanese journal of radiology2020

Delineation of the nerve fiber bundles of the infant brain associated with aging using phase difference-enhanced imaging: a preliminary study.

Hiroyuki Fujii, Noriko Sato, Yukio Kimura, Atsuhiko Sugiyama, Yoko Shigemoto, Fumio Suzuki, Hiroshi Matsuda, Masayuki Sasaki, Hideharu Sugimoto

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In one paragraph

Article in Japanese journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hiroyuki FujiiDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-0031, Japan.
Noriko SatoDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-0031, Japan. snoriko@ncnp.go.jp.
Yukio KimuraDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-0031, Japan.
Atsuhiko SugiyamaDepartment of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yoko ShigemotoDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-0031, Japan.
Fumio SuzukiDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-0031, Japan.
Hiroshi MatsudaIntegrative Brain Imaging Center, National Center of Neurology and Psychiatry, Tokyo, Japan.
Masayuki SasakiDepartment of Child Neurology, National Center of Neurology and Psychiatry, Tokyo, Japan.
Hideharu SugimotoDepartment of Radiology, School of Medicine, Jichi Medical University, Tochigi, Japan.
National Center of Neurology and Psychiatry · JPChiba University · JPJichi Medical University · JP

Funding

Kawano Foundation for medical research, Japan 27-waka-12
6 · The paper itself

Abstract

purposeThe purpose of this study was to evaluate the delineation of nerve fiber bundles in the brainstem and optic radiation in infants associated with aging on T1WI, T2WI, and phase difference-enhanced (PADRE) images. MATERIALS AND

methodsWe retrospectively reviewed 21 consecutive subjects < 2 years old who underwent brain MRI without abnormal imaging findings. Two neuroradiologists evaluated the eight nerve fiber bundles in the brainstem and optic radiation using a 3-point scale focused on the contrast to surrounding brain parenchyma. We also evaluated the signal ratio of the optic radiation to surrounding white matter on PADRE for each month age.

resultsT2WI was able to delineate nerve fiber bundles better than T1WI at 1 month old, and the images gradually became unclear with aging. On PADRE, almost all nerve fiber bundles were unclear or invisible at 1 month old but gradually became clearer with aging. There was a significant negative correlation between age and the signal ratio of the optic radiation to surrounding white matter.

conclusionsThe PADRE imaging was able to delineate the nerve fiber bundles in infants, and the delineation gradually became clearer with aging. The combination of PADRE, T1WI, and T2WI would be useful for evaluation of nerve fiber bundles in infants.

Indexed as

AdultAgingBrainFemaleHumansImage Processing, Computer-AssistedInfantInfant, NewbornMagnetic Resonance ImagingMaleNerve FibersRetrospective StudiesMRIPADREPhase difference-enhanced imaging

Identifiers

PMID32232647
OpenAlexW3014043362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.