Evidence map›Paper›PMID 32232634›Full record

Observational studyPediatric nephrology (Berlin, Germany)2020

Incidence, risk factors, and outcomes of acute kidney injury in neonates after surgical procedures.

Yang Wu, Xintian Hua, Gang Yang, Bo Xiang, Xiaoping Jiang

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  8. Review
  9. Timing and risk factors associated with acute kidney injury in infants with necrotizing enterocolitis.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  10. Article
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  15. Review
  16. Clinical impact of severe acute kidney injury on post-operative and brain injury outcomes in preterm infants following surgical necrotizing enterocolitis.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2022
    Article
  17. Inadvertent hypothermia and acute kidney injury (AKI) in neonates undergoing gastrointestinal surgeries: a retrospective study.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Article
  18. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yang WuDepartment of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
Xintian HuaDepartment of Neonatology, West China Second Hospital, Sichuan University, Chengdu, China.
Gang YangDepartment of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
Bo XiangDepartment of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
Xiaoping JiangDepartment of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China. jxpps_wc@sina.com.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is common and associated with poor outcomes in critically ill neonates. The objective of this study was to study the incidence, risk factors, and clinical outcomes of AKI in neonates receiving non-cardiac surgery.

methodsWe performed a single-center retrospective study between January 2017 and December 2018 of neonates who had received abdominal and thoracic surgical procedures. AKI was defined by the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Patient information, clinical data, and outcomes were collected and analyzed. Logistic regression was used to analyze risk factors of AKI and association between AKI and mortality.

resultsFifty-four (33.8%) of 160 patients developed AKI after surgical procedures. Compared with neonates without AKI, neonates with AKI had higher mortality rate (18.5% VS 5.7%, p = 0.022), lower gestational age (30.5 weeks, interquartile range [IQR] 28-33.5, VS 34.5 weeks, IQR 33-37.5, p = 0.035), higher rates of very low birth weight (33.3% VS 17.0%, p = 0.019), longer duration of mechanical ventilation (0.5 days, IQR 0-1.5, VS 0 days, IQR 0-1, p = 0.043) and higher rates of sepsis (35.2% VS 19.8%, p = 0.034). Risk factors of AKI included gestational age under 32 weeks (OR 4.8, 95% CI 1.8-12.6; p = 0.001), sepsis (OR 4.3, 95% CI 1.7-11.3; p = 0.003), operation time longer than 120 min (OR 2.7, 95% CI 1.1-6.6; p = 0.024), and diagnosis of necrotizing enterocolitis (OR 3.5, 95% CI 1.3-9.1; p = 0.011). AKI after surgery was significantly associated with mortality (OR 4.3, 95% CI 1.1-16.9; p = 0.036).

conclusionsAKI is common and associated with poor outcomes in surgical neonates. Early recognition and intervention of AKI in these patients are important.

Indexed as

Acute Kidney InjuryCase-Control StudiesChinaDigestive System Surgical ProceduresEnterocolitis, NecrotizingFemaleHumansIncidenceInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureInfant, Very Low Birth WeightMaleOperative TimePostoperative ComplicationsRetrospective StudiesAcute kidney injuryNeonatal surgeryOutcomeRisk factor

Identifiers

PMID32232634
OpenAlexW3013880874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.