Evidence map›Paper›PMID 32232406›Full record

ReviewThe Journal of nutrition2020

Does Consumption of Fermented Foods Modify the Human Gut Microbiota?

Leah T Stiemsma, Reine E Nakamura, Jennifer G Nguyen, Karin B Michels

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05900609 (Gut Health Enhancement by Eating Favourable Food), which is not on this map. Cited by 77 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 3 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05900609 nacompletednot on this mapstarted 2023, after this paper: background citation

Gut Health Enhancement by Eating Favourable Food

TypeinterventionalSponsorVU University of AmsterdamRan2023 to 2024Enrolled146ConditionsMicrobial ColonizationArmsWholeFiber, Kombucha, Maltodextrin DE19/21
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 3 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
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  11. Bibliometric Analysis on and Characteristics in Soy Yogurt.Probiotics and antimicrobial proteins · 2026
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Leah T StiemsmaDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
Reine E NakamuraDepartment of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA.
Jennifer G NguyenDepartment of Biology, University of California, Los Angeles, CA, USA.
Karin B MichelsDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
University of California, Los Angeles · USUniversity of Freiburg · DE

Funding

UCLA CANCER EPIDEMIOLOGY TRAINING PROGRAMT32CA009142 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1986 to 2024
$6.3M
NCI NIH HHS T32 CA009142
6 · The paper itself

Abstract

The human microbiota is a key contributor to many aspects of human health and its composition is largely influenced by diet. There is a growing body of scientific evidence to suggest that gut dysbiosis (microbial imbalance of the intestine) is associated with inflammatory and immune-mediated diseases (e.g., inflammatory bowel disease and asthma). Regular consumption of fermented foods (e.g., kimchi, kefir, etc.) may represent a potential avenue to counter the proinflammatory effects of gut dysbiosis. However, an assessment of the available literature in this research area is lacking. Here we provide a critical review of current human intervention studies that analyzed the effect of fermented foods on the composition and/or function of the human gut microbiota. A total of 19 human intervention studies were identified that met this search criteria. In this review, we discuss evidence that consumption of fermented foods may modify the gut microbiota in humans. Further, there is cursory evidence to suggest that gut microbiota compositional changes mediate associations between fermented food consumption and human health outcomes. Although promising, there remains considerable heterogeneity in the human populations targeted in the intervention studies we identified. Larger longitudinal feeding studies with longer follow-up are necessary to confirm and enhance the current data. Further, future studies should consider analyzing microbiota function as a means to elucidate the mechanism linking fermented food consumption with human health. This review highlights methodologic considerations for intervention trials, emphasizing an expanse of research opportunities related to fermented food consumption in humans.

Indexed as

Fermented FoodsGastrointestinal MicrobiomeBacteriaHumansfermented foodslactic acid bacteriamicrobiotaprobioticsyogurt

Identifiers

PMID32232406
PMCPMC7330458
OpenAlexW3013188026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.