Evidence map›Paper›PMID 32232386›Full record

ReviewInflammatory bowel diseases2020

Resolution of Inflammation and Gut Repair in IBD: Translational Steps Towards Complete Mucosal Healing.

Gwo-Tzer Ho, Jennifer A Cartwright, Emily J Thompson, Calum C Bain, Adriano G Rossi

Open access · bronzeAbstract readReview
In one paragraph

Review in Inflammatory bowel diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
  2. Article
  3. Biomaterials and biosystems · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. LiveFoods (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gwo-Tzer HoEdinburgh IBD Science Unit, Centre for Inflammation Research, Queen's Medical Research Unit, University of Edinburgh, Scotland, United Kingdom.
Jennifer A CartwrightEdinburgh IBD Science Unit, Centre for Inflammation Research, Queen's Medical Research Unit, University of Edinburgh, Scotland, United Kingdom.
Emily J ThompsonEdinburgh IBD Science Unit, Centre for Inflammation Research, Queen's Medical Research Unit, University of Edinburgh, Scotland, United Kingdom.
Calum C BainEdinburgh IBD Science Unit, Centre for Inflammation Research, Queen's Medical Research Unit, University of Edinburgh, Scotland, United Kingdom.
Adriano G RossiEdinburgh IBD Science Unit, Centre for Inflammation Research, Queen's Medical Research Unit, University of Edinburgh, Scotland, United Kingdom.
Queen's Medical Centre · GB

Funding

Chief Scientist OfficeMedical Research Council MR/K013386/1Medical Research Council MRNO2995X/1Wellcome TrustWellcome Trust 108906/Z/15/ZWellcome Trust 206234/Z/17/Z
6 · The paper itself

Abstract

Despite significant recent therapeutic advances, complete mucosal healing remains a difficult treatment target for many patients with inflammatory bowel diseases (IBD) to achieve. Our review focuses on the translational concept of promoting resolution of inflammation and repair as a necessary adjunctive step to reach this goal. We explore the roles of inflammatory cell apoptosis and efferocytosis to promote resolution, the new knowledge of gut monocyte-macrophage populations and their secreted prorepair mediators, and the processes of gut epithelial repair and regeneration to bridge this gap. We discuss the need and rationale for this vision and the tangible steps toward integrating proresolution therapies in IBD.

Indexed as

Anti-Inflammatory AgentsHumansImmune System PhenomenaInflammationInflammation MediatorsInflammatory Bowel DiseasesIntestinal MucosaAnti-Inflammatory AgentsInflammation MediatorsCrohninflammationinflammatory bowel diseasemucosal healingulcerative colitis

Identifiers

PMID32232386
PMCPMC7365805
OpenAlexW3013611104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.