Evidence map›Paper›PMID 32232144›Full record

ArticleACS central science2020

Multicolor Polymeric Nanoparticle Neuronal Tracers.

Nanzhi Zang, John B Issa, Treffly B Ditri, Dante S Bortone, Mollie A Touve, Anthony M Rush, Massimo Scanziani, Daniel A Dombeck, Nathan C Gianneschi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS central science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nanzhi ZangDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
John B IssaDepartment of Neurobiology, Northwestern University, Evanston, Illinois 60208, United States.
Treffly B DitriDepartment of Chemistry & Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.
Dante S BortoneDepartment of Neurobiology, University of California, San Diego, La Jolla, California 92093, United States.
Mollie A TouveDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Anthony M RushDepartment of Chemistry & Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.
Massimo ScanzianiDepartment of Neurobiology, University of California, San Diego, La Jolla, California 92093, United States.
Daniel A DombeckDepartment of Neurobiology, Northwestern University, Evanston, Illinois 60208, United States.
Nathan C GianneschiDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Northwestern University · USUniversity of California San Diego · USHoward Hughes Medical Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deciphering the targets of axonal projections plays a pivotal role in interpreting neuronal function and pathology. Neuronal tracers are indispensable tools for uncovering the functions and interactions between different subregions of the brain. However, the selection of commercially available neuronal tracers is limited, currently comprising small molecule dyes, viruses, and a handful of synthetic nanoparticles. Here, we describe a series of polymer-based nanoparticles capable of retrograde transport along neurons

Identifiers

PMID32232144
PMCPMC7099585
OpenAlexW3006733190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.