ArticleACS central science2020
Bottlebrush Bridge between Soft Gels and Firm Tissues.
Article in ACS central science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Bottlebrush Polyolefin Sulfones as Triggerable and Degradable Pressure-Sensitive Adhesives.Angewandte Chemie (International ed. in English) · 2026Article
- A Superstrong and Ultratough Stretchable Electronic Conductor With Ultradurable Strain-Insensitive Electromechanical Performance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Applications of a continuum model for brush gels.International journal of solids and structures · 2026Article
- Article
- Gelation Dynamics in Polydimethylsiloxane Bottlebrush Elastomers.Macromolecular rapid communications · 2025Article
- Branched Polymer Architecture for Modulating Interactions in Material-Bio Interface.Tissue engineering and regenerative medicine · 2025Review
- Molecular Structure of Foldable Bottlebrush Polymers in Melts.Macromolecules · 2025Article
- A universal strategy for decoupling stiffness and extensibility of polymer networks.Science advances · 2024Article
- Revealing Long-Range Order in Brush-like Graft Copolymers Through In Situ Measurements of X-Ray Scattering During Deformation.Polymers · 2024Article
- Integrating Mechanics and Bioactivity: A Detailed Assessment of Elasticity and Viscoelasticity at Different Scales in 2D Biofunctionalized PEGDA Hydrogels for Targeted Bone Regeneration.ACS applied materials & interfaces · 2024Article
- Nonlinear Elastic Bottlebrush Polymer Hydrogels Modulate Actomyosin Mediated Protrusion Formation in Mesenchymal Stromal Cells.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Bottlebrush Networks: A Primer for Advanced Architectures.Angewandte Chemie (International ed. in English) · 2024Review
- Inorganic Bottlebrush and Comb Polymers as a Platform for Supersoft, Solvent-Free Elastomers.ACS polymers Au · 2024Article
- 3D printable soft and solvent-free thermoplastic elastomer containing dangling bottlebrush chains.Materials advances · 2023Article
- Conductive and elastic bottlebrush elastomers for ultrasoft electronics.Nature communications · 2023Article
- Pendant Group Modifications Provide Graft Copolymer Silicones with Exceptionally Broad Thermomechanical Properties.ACS central science · 2023Article
- The Impact of Polymerization Chemistry on the Mechanical Properties of Poly(dimethylsiloxane) Bottlebrush Elastomers.Macromolecules · 2022Article
- Synthesis of well-defined linear-bottlebrush-linear triblock copolymer towards architecturally-tunable soft materials.Polymer chemistry · 2022Article
- Fatigue-free artificial ionic skin toughened by self-healable elastic nanomesh.Nature communications · 2022Article
- Bottlebrush Amphiphilic Polymer Co-Networks.Macromolecules · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Softness and firmness are seemingly incompatible traits that synergize to create the unique soft-yet-firm tactility of living tissues pursued in soft robotics, wearable electronics, and plastic surgery. This dichotomy is particularly pronounced in tissues such as fat that are known to be both ultrasoft and ultrafirm. However, synthetically replicating this mechanical response remains elusive since ubiquitously employed soft gels are unable to concurrently reproduce tissue firmness. We have addressed the tissue challenge through the self-assembly of linear-bottlebrush-linear (LBL) block copolymers into thermoplastic elastomers. This hybrid molecular architecture delivers a hierarchical network organization with a cascade of deformation mechanisms responsible for initially low moduli followed by intense strain-stiffening. By bridging the firmness gap between gels and tissues, we have replicated the mechanics of fat, fetal membrane, spinal cord, and brain tissues. These solvent-free, nonleachable, and tissue-mimetic elastomers also show enhanced biocompatibility as demonstrated by cell proliferation studies, all of which are vital for the safety and longevity of future biomedical devices.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.