ReviewOrthopaedic journal of sports medicine2020
Perioperative Blood Flow Restriction Rehabilitation in Patients Undergoing ACL Reconstruction: A Systematic Review.
Review in Orthopaedic journal of sports medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 32 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Bone Health on Landing Mechanics on Patients Post ACL Reconstruction.
Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation
Effect of Blood Flow Restriction (BFR) on Rehabilitation Protocols Following Anterior Cruciate Ligament Reconstruction (ACLR) With Quadricep Autograft
Who cites it
32 citing papers in PubMed, 7 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Blood flow restriction training for lower limb injury prevention and rehabilitation in dancers: a scoping review of current evidence and future directions.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Summary of the best evidence on blood flow restriction training for patients after anterior cruciate ligament reconstruction surgery.Frontiers in rehabilitation sciences · 2026Pooled it
- Effects of blood flow restriction training on patients with chronic ankle instability: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Effectiveness of Blood Flow Restriction on Functionality, Quality of Life and Pain in Patients with Neuromusculoskeletal Pathologies: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- ACL Reconstruction: Which Additional Physiotherapy Interventions Improve Early-Stage Rehabilitation? A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Effect of Blood Flow Restriction on Functional, Physiological and Structural Variables of Muscle in Patients with Chronic Pathologies: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Pooled it
- The effectiveness and safety of blood flow restriction training for the post-operation treatment of distal radius fracture.Annals of medicine · 2023Trial
- The Effectiveness of Blood Flow Restriction Training on Rehabilitation After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Blood Flow Restriction Training Prior to and After Anterior Cruciate Ligament Reconstruction: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Optimizing return to sports after anterior cruciate ligament reconstruction: A multi-factorial umbrella review on rehabilitation strategies.Journal of clinical orthopaedics and trauma · 2025Review
- The effect of blood flow restricted exercise on measures of health and physical fitness across all populations: An umbrella review and meta-meta-analysis.Sports medicine and health science · 2025Review
- Development and usability testing of a preliminary web-based application for the clinical implementation of blood flow restriction: a mixed methods pilot study.Frontiers in physiology · 2025Article
- Mechanisms of blood flow restriction training for knee pain: a mini review.Frontiers in physiology · 2025Review
- Blood Flow Restriction Training in the Young Athlete.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2024Article
- Outcomes of Blood Flow Restriction Training After ACL Reconstruction in NCAA Division I Athletes.Orthopaedic journal of sports medicine · 2024Article
- Short-Term Impact of Low-Intensity Exercise with Blood Flow Restriction on Mild Knee Osteoarthritis in Older Adults: A Pilot Study.Healthcare (Basel, Switzerland) · 2024Article
- Oh, My Quad: A Clinical Commentary And Evidence-Based Framework for the Rehabilitation of Quadriceps Size and Strength after Anterior Cruciate Ligament Reconstruction.International journal of sports physical therapy · 2024Article
- Effects of a Perioperative Blood Flow Restriction Therapy Program on Early Quadriceps Strength and Patient-Reported Outcomes After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2023Article
- Early- and Late-Stage Benefits of Blood Flow Restriction Training on Knee Strength in Adolescents After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow-load blood flow restriction (BFR) training has attracted attention as a potentially effective method of perioperative clinical rehabilitation for patients undergoing orthopaedic procedures. PURPOSE: To (1) compare the effectiveness of low-load BFR training in conjunction with a standard rehabilitation protocol, pre- and postoperatively, and non-BFR interventions in patients undergoing anterior cruciate ligament reconstruction (ACLR) and (2) evaluate protocols for implementing BFR perioperatively for patients undergoing ACLR. STUDY
designSystematic review; Level of evidence, 2.
methodsA systematic review of the 3 medical literature databases was conducted to identify all level 1 and 2 clinical trials published since 1990 on BFR in patients undergoing ACLR. Patient demographics from included studies were pooled. Outcome data were documented, including muscle strength and size, and perceived pain and exertion. A descriptive analysis of outcomes from BFR and non-BFR interventions was performed.
resultsA total of 6 studies (154 patients; 66.2% male; mean ± SD age, 24.2 ± 3.68 years) were included. Of these, 2 studies examined low-load BFR as a preoperative intervention, 1 of which observed a significant increase in muscle isometric endurance (
conclusionThis systematic review found evidence on the topic of BFR rehabilitation after ACLR to be sparse and heterogeneous likely because of the relatively recent onset of its popularity. While a few authors have demonstrated the potential strength and hypertrophy benefits of perioperative BFR, future investigations with standardized outcomes, long-term follow-up, and more robust sample sizes are required to draw more definitive conclusions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.