ReviewFrontiers in cardiovascular medicine2020
Timing of Circulatory and Neurological Events in Syncope.
Review in Frontiers in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- Orthostatic hypotension and complaints: not a clear-cut relation.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Prediction evaluation of the Tp-Te interval in patients with vasovagal syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Evaluation of the Choroidal Thickness and Retinal Nerve Fiber Layer Thickness in Patients with Vasovagal Syncope.Journal of personalized medicine · 2025Article
- Features of Clinical Manifestations and Heart Rate Variability in Children with Malignant Vasovagal Syncope.Children (Basel, Switzerland) · 2025Article
- Haemodynamic Patterns in Reflex Syncope: Insights from Head-Up Tilt Tests in Adults and Children.Journal of clinical medicine · 2025Article
- Malignant vasovagal syncope in children.World journal of pediatrics : WJP · 2025Review
- Cardiac Geometry and Function in Patients with Reflex Syncope.Journal of clinical medicine · 2024Review
- Rapid changes in cerebrovascular compliance during vasovagal syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Article
- Article
- Predictive value of isolated very low QRS voltage in tilt-table test for neurally mediated syncope.SAGE open medicine · 2024Article
- Variability of cardioinhibition in vasovagal syncope: differences between subgroups during cardioinhibition and beyond.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Article
- Article
- Changes in Blood Pressure Variability in Children with Postural Tachycardia Syndrome.Children (Basel, Switzerland) · 2023Article
- Pediatric syncope: pearls and pitfalls in history taking.Clinical and experimental pediatrics · 2023Article
- A review of the DTS: Diathermic Syncope® system with a discussion regarding its use for kosher slaughter (Animal welfare (South Mimms, England) · 2023Review
- Diagnosis and treatment of orthostatic hypotension.The Lancet. Neurology · 2022Review
- Orthostatic stress response in pediatric Fontan patients and the effect of ACE inhibition.PloS one · 2022Article
- Autonomic manifestations of epilepsy: emerging pathways to sudden death?Nature reviews. Neurology · 2021Review
- Timing of syncope in ictal asystole as a guide when considering pacemaker implantation.Journal of cardiovascular electrophysiology · 2021Article
- Towards Understanding the Genetic Nature of Vasovagal Syncope.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Syncope usually lasts less than a minute, in which short time arterial blood pressure temporarily falls enough to decrease brain perfusion so much that loss of consciousness ensues. Blood pressure decreases quickest when the heart suddenly stops pumping, which happens in arrhythmia and in severe cardioinhibitory reflex syncope. Loss of consciousness starts about 8 s after the last heart beat and circulatory standstill occurs after 10-15 s. A much slower blood pressure decrease can occur in syncope due to orthostatic hypotension Standing blood pressure can then stabilize at low values often causing more subtle signs (i.e., inability to act) but often not low enough to cause loss of consciousness. Cerebral autoregulation attempts to keep cerebral blood flow constant when blood pressure decreases. In reflex syncope both the quick blood pressure decrease and its low absolute value mean that cerebral autoregulation cannot prevent syncope. It has more protective value in orthostatic hypotension. Neurological signs are related to the severity and timing of cerebral hypoperfusion. Several unanswered pathophysiological questions with possible clinical implications are identified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.