Evidence map›Paper›PMID 32231873›Full record

ArticlePeerJ2020

Genomic analysis of variability in Delta-toxin levels between

Michelle Su, James T Lyles, Robert A Petit Iii, Jessica Peterson, Michelle Hargita, Huaqiao Tang, Claudia Solis-Lemus, Cassandra L Quave, Timothy D Read

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. The Joint Action of Bacteriophage and Antibiotics in the Treatment ofbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. The role of innate immunity, antibiotics, and bacteriophages in the course of bacterial infections and their treatment.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Journal of bacteriology · 2025
    Article
  5. Article
  6. Review
  7. Antibiotic killing of drug-induced bacteriostatic cells.Antimicrobial agents and chemotherapy · 2025
    Article
  8. Antibiotic killing of drug-induced bacteriostatic cells.bioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Average Nucleotide Identity basedbioRxiv : the preprint server for biology · 2024
    Article
  11. Genotypes ofToxins · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Michelle SuDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, GA, United States of America.
James T LylesCenter for the Study of Human Health, College of Arts and Sciences, Emory University, Atlanta, GA, United States of America.
Robert A Petit IiiDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, GA, United States of America.
Jessica PetersonDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, GA, United States of America.
Michelle HargitaDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, GA, United States of America.
Huaqiao TangCenter for the Study of Human Health, College of Arts and Sciences, Emory University, Atlanta, GA, United States of America.
Claudia Solis-LemusDepartment of Human Genetics, School of Medicine, Emory University, Atlanta, GA, United States of America.
Cassandra L QuaveCenter for the Study of Human Health, College of Arts and Sciences, Emory University, Atlanta, GA, United States of America.
Timothy D ReadDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, GA, United States of America.
Emory University · US

Funding

Antimicrobial Resistance and Therapeutic Discovery Training ProgramT32AI106699 · NIAID · EMORY UNIVERSITY · PI Graeme L Conn, Joanna B Goldberg · 2014 to 2026
$2.7M
Genomics-based prediction of antibiotic failure in S. aureus infectionsR21AI121860 · NIAID · EMORY UNIVERSITY · PI READ, TIMOTHY D., SATOLA, SARAH W · 2016 to 2017
$429k
NIAID NIH HHS R21 AI121860NIAID NIH HHS T32 AI106699
6 · The paper itself

Abstract

backgroundThe delta-toxin (δ-toxin) of

methodsA set of 124

resultsThe

conclusionsThe amount of stationary phase production of the toxin is a strain-specific phenotype likely affected by a complex interaction of number of genes with different levels of effect. We discovered new candidate genes that potentially play a role in modulating production. We report for the first time that the product of the

Indexed as

Bacterial GWASDelta-toxinGenome-based predictorStaphylococcus aureus

Identifiers

PMID32231873
PMCPMC7100594
OpenAlexW3013147049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.