Evidence map›Paper›PMID 32231639›Full record

ReviewFrontiers in endocrinology2020

Update on Fundamental Mechanisms of Thyroid Cancer.

Alessandro Prete, Patricia Borges de Souza, Simona Censi, Marina Muzza, Nicole Nucci, Marialuisa Sponziello

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 282 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
282citing papers in PubMed, 4 pooled it
33.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

282 citing papers in PubMed, 4 syntheses or guidelines pooled it, 461 citations in OpenAlex.

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222 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Alessandro PreteUnit of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Patricia Borges de SouzaSection of Endocrinology and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Simona CensiEndocrinology Unit, Department of Medicine (DIMED), University of Padova, Padova, Italy.
Marina MuzzaDivision of Endocrinology and Metabolism IRCCS Istituto Auxologico Italiano, Milan, Italy.
Nicole NucciDepartment of Medicine, University of Perugia, Perugia, Italy.
Marialuisa SponzielloDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITSapienza University of Rome · ITUniversity of Ferrara · ITUniversity of Padua · ITUniversity of Perugia · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of thyroid cancer (TC) has increased worldwide over the past four decades. TC is divided into three main histological types: differentiated (papillary and follicular TC), undifferentiated (poorly differentiated and anaplastic TC), and medullary TC, arising from TC cells. This review discusses the molecular mechanisms associated to the pathogenesis of different types of TC and their clinical relevance. In the last years, progresses in the genetic characterization of TC have provided molecular markers for diagnosis, risk stratification, and treatment targets. Recently, papillary TC, the most frequent form of TC, has been reclassified into two molecular subtypes, named

Indexed as

Carcinoma, NeuroendocrineGenetic Predisposition to DiseaseHumansMutationPrognosisProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-retThyroid Cancer, PapillaryThyroid NeoplasmsThyroid NoduleTumor MicroenvironmentProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-retBRAFoncogenesRASRETthyroid cancer

Identifiers

PMID32231639
PMCPMC7082927
OpenAlexW3012017822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.