Evidence map›Paper›PMID 32231536›Full record

ArticleCase reports in oncology

Treatment of Rectal Cancer-Induced Disseminated Carcinomatosis of the Bone Marrow with FOLFOX plus Cetuximab and Panitumumab.

Takehito Ehara, Masato Kitazawa, Nao Hondo, Shugo Takahata, Yuta Yamamoto, Makoto Koyama, Motohiro Okumura, Satoshi Nakamura, Shigeo Tokumaru, Futoshi Muranaka and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Takehito EharaDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Masato KitazawaDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Nao HondoDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Shugo TakahataDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Yuta YamamotoDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Makoto KoyamaDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Motohiro OkumuraDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Satoshi NakamuraDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Shigeo TokumaruDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Futoshi MuranakaDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Yusuke MiyagawaDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Yuji SoejimaDepartment of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Shinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated carcinomatosis of the bone marrow (DCBM) in colorectal cancer is an extremely rare complication with a poor prognosis. Here, we report a case of DCBM due to rectal cancer successfully treated with a combination of FOLFOX and an anti-epidermal growth factor receptor (EGFR) agent. The patient was a 38-year-old man diagnosed with rectal cancer with multiple bone and para-aortic lymph node metastases complicated by disseminated intravascular coagulation (DIC). He first recovered from DIC following cotreatment with FOLOX plus cetuximab; subsequently, the second attack was successfully treated with FOLFOX plus panitumumab. His initial condition was extremely poor, but he survived with two FOLFOX plus anti-EGFR regimens and died 333 days after introduction of chemotherapy.

Indexed as

CetuximabColorectal cancerDisseminated carcinomatosis of the bone marrowPanitumumab

Identifiers

PMID32231536
PMCPMC7098366
OpenAlexW3007852922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.