Evidence map›Paper›PMID 32231351›Full record

ArticlePLoS computational biology2020

ProteinVR: Web-based molecular visualization in virtual reality.

Kevin C Cassidy, Jan Šefčík, Yogindra Raghav, Alexander Chang, Jacob D Durrant

Abstract read
In one paragraph

Article in PLoS computational biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Elements and roadmap for interactive molecular graphics and modeling "in the Holodeck".Protein science : a publication of the Protein Society · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. A Concise Review of Biomolecule Visualization.Current issues in molecular biology · 2024
    Review
  9. Article
  10. Article
  11. Extended reality for biomedicine.Nature reviews. Methods primers · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Bioinformatics and the Metaverse: Are We Ready?Frontiers in bioinformatics · 2022
    Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kevin C CassidyDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Jan ŠefčíkFaculty of Information Technology, Czech Technical University in Prague, Prague, Czech Republic.
Yogindra RaghavDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0002-1285-6397
Alexander ChangDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0002-3822-0469
Jacob D DurrantDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0002-5808-4097

Funding

Advancing drug-lead and chemical-probe discovery using weighted-ensemble simulations and biophysical validationR01GM132353 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DURRANT, JACOB D · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM132353
6 · The paper itself

Abstract

Protein structure determines biological function. Accurately conceptualizing 3D protein/ligand structures is thus vital to scientific research and education. Virtual reality (VR) enables protein visualization in stereoscopic 3D, but many VR molecular-visualization programs are expensive and challenging to use; work only on specific VR headsets; rely on complicated model-preparation software; and/or require the user to install separate programs or plugins. Here we introduce ProteinVR, a web-based application that works on various VR setups and operating systems. ProteinVR displays molecular structures within 3D environments that give useful biological context and allow users to situate themselves in 3D space. Our web-based implementation is ideal for hypothesis generation and education in research and large-classroom settings. We release ProteinVR under the open-source BSD-3-Clause license. A copy of the program is available free of charge from http://durrantlab.com/protein-vr/, and a working version can be accessed at http://durrantlab.com/pvr/.

Indexed as

InternetProteinsVirtual RealityComputational BiologyImaging, Three-DimensionalProtein ConformationProteins

Identifiers

PMID32231351
PMCPMC7147804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.