Evidence map›Paper›PMID 32231280›Full record

SynthesisNature human behaviour2020

Systematic review and meta-analysis investigating moderators of long-term effects of exercise on cognition in healthy individuals.

Sebastian Ludyga, Markus Gerber, Uwe Pühse, Vera N Looser, Keita Kamijo

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Nature human behaviour, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 212 papers, 31 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
212citing papers in PubMed, 31 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

212 citing papers in PubMed, 31 syntheses or guidelines pooled it.

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152 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Sebastian LudygaDepartment of Sport, Exercise and Health, University of Basel, Basel, Switzerland. ebastian.ludyga@unibas.ch.ORCID http://orcid.org/0000-0002-3905-7894
Markus GerberDepartment of Sport, Exercise and Health, University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0001-6140-8948
Uwe PühseDepartment of Sport, Exercise and Health, University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0003-1228-316X
Vera N LooserDepartment of Sport, Exercise and Health, University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-6878-8469
Keita KamijoUniversity of Tsukuba, Tsukuba, Japan.ORCID http://orcid.org/0000-0001-8828-4930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As cognitive function is linked with academic achievement, career success and mental health, there is a need to understand how the cognitive benefits of long-term exercise can be optimized. Our meta-regression included 80 randomized controlled trials and examined moderators of the effects of exercise on cognition in healthy individuals. The summary effect was small and did not differ between cognitive domains. Higher benefits of exercise on cognitive function were found after coordinative exercise compared with other exercise types. With longer intervention length, the effect size increased with longer session duration. Exercise was less effective in female compared with male individuals, and the dose-response relationship differed between sexes. Our findings suggest a general rather than domain-specific effect of exercise on cognition, which is influenced by sex, exercise type and reciprocal relationships between dose parameters. We derive sex-specific recommendations on how cognitive benefits can be optimized by exercise intensity, its progression and exercise type.

Indexed as

CognitionExerciseFemaleHumansMaleSex Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.