SynthesisNature human behaviour2020
Systematic review and meta-analysis investigating moderators of long-term effects of exercise on cognition in healthy individuals.
Synthesis in Nature human behaviour, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 212 papers, 31 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
212 citing papers in PubMed, 31 syntheses or guidelines pooled it.
- Effects of Acute and Chronic Physical Exercise on Esports Performance: A Systematic Review.Sports medicine - open · 2026Pooled it
- Domain-general behavioral gains and neural correlates of cognitive training in healthy populations: a neuroimaging meta-analysis.Behavioral and brain functions : BBF · 2026Pooled it
- Effects of exercise on executive function in cognitively healthy older adults: a systematic review and three-level meta-analysis.BMC public health · 2026Pooled it
- Cognitive training in neurological disorders: meta-analytic evidence for behavioral gains and neural correlates.Behavioral and brain functions : BBF · 2026Pooled it
- A systematic review of exercise interventions on negative affect, pain, and fatigue in women with premenstrual syndrome.BMC women's health · 2026Pooled it
- Pooled it
- Effects of exercise intervention on executive function in college students: a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2026Pooled it
- An ALE meta-analysis on the effects of neural changes due to exercise on executive function in a healthy population.Scientific reports · 2025Pooled it
- A review of the 257 meta-analyses of the differences between females and males in prevalence and risk, protective factors, and treatment outcomes for mental disorder.BMC psychiatry · 2025Pooled it
- Systematic review on the effects of exercise with and without breakfast consumption on cognitive performance in healthy adults.BMC psychology · 2025Pooled it
- Systematic review and meta-analysis of the effects of EEG neurofeedback combined with pharmacological treatment on the positive and negative symptoms in patients with schizophrenia.Frontiers in psychiatry · 2025Pooled it
- Pooled it
- Effect of non-invasive brain stimulation on cognitive function and activities of daily living in patients with carbon monoxide poisoning: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Meta-analysis of the effectiveness of exercise as an intervention for suicidal tendency in depressed patients.Frontiers in psychology · 2025Pooled it
- Pooled it
- Effects of Aerobic Exercise on Cardiopulmonary Function in Postoperative Patients with Congenital Heart Disease: A Meta-analysis.Reviews in cardiovascular medicine · 2024Pooled it
- Effect of music therapy on anxiety and depression in breast cancer patients: systematic review and meta-analysis.Scientific reports · 2024Pooled it
- The Effectiveness of Dance Interventions on Psychological and Cognitive Health Outcomes Compared with Other Forms of Physical Activity: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Effects of physical exercise on anxiety depression and emotion regulation in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis.Frontiers in pediatrics · 2024Pooled it
- Alexa, let's train now! - A systematic review and classification approach to digital and home-based physical training interventions aiming to support healthy cognitive aging.Journal of sport and health science · 2024Pooled it
152 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As cognitive function is linked with academic achievement, career success and mental health, there is a need to understand how the cognitive benefits of long-term exercise can be optimized. Our meta-regression included 80 randomized controlled trials and examined moderators of the effects of exercise on cognition in healthy individuals. The summary effect was small and did not differ between cognitive domains. Higher benefits of exercise on cognitive function were found after coordinative exercise compared with other exercise types. With longer intervention length, the effect size increased with longer session duration. Exercise was less effective in female compared with male individuals, and the dose-response relationship differed between sexes. Our findings suggest a general rather than domain-specific effect of exercise on cognition, which is influenced by sex, exercise type and reciprocal relationships between dose parameters. We derive sex-specific recommendations on how cognitive benefits can be optimized by exercise intensity, its progression and exercise type.
Indexed as
Identifiers
32231280What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.