ArticleScientific reports2020
Gut, oral and skin microbiome of Indian patrilineal families reveal perceptible association with age.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Global Microbiome: Core and Unique Signatures Across Diverse Populations.International journal of molecular sciences · 2026Pooled it
- Nationality and body location alter human skin microbiome.Applied microbiology and biotechnology · 2021Pooled it
- Altered Salivary Microbiota Following Bifidobacterium animalis Subsp. Lactis BL-11 Supplementation Are Associated with Anthropometric Growth and Social Behavior Severity in Individuals with Prader-Willi Syndrome.Probiotics and antimicrobial proteins · 2022Trial
- Gut microbiomes of tribal communities in India vary with dairy and grain consumption.Gut microbes · 2026Article
- Age-adjusted machine learning identifies facial skin microbes associated with skin quality among Korean women.mSystems · 2026Article
- Article
- Integrative insights into the oral microbiome's role in systemic diseases: novel therapeutic strategies and future directions.Antonie van Leeuwenhoek · 2025Review
- Chronological age estimation from human microbiomes with transformer-based Robust Principal Component Analysis.Communications biology · 2025Article
- Skin microbiome-biophysical association: a first integrative approach to classifying Korean skin types and aging groups.Frontiers in cellular and infection microbiology · 2025Article
- Skin microbiota variation in Indian families.PeerJ · 2025Article
- Identification of age-associated microbial changes via long-read 16S sequencing.Gut pathogens · 2024Article
- Daily occupational exposure in swine farm alters human skin microbiota and antibiotic resistome.iMeta · 2024Article
- Gut microbial ecology and exposome of a healthy Pakistani cohort.Gut pathogens · 2024Article
- The increasing importance of the oral microbiome in periodontal health and disease.Future science OA · 2023Review
- Haze Exposure Changes the Skin Fungal Community and Promotes the Growth ofMicrobiology spectrum · 2023Article
- The dynamic balance of the skin microbiome across the lifespan.Biochemical Society transactions · 2023Review
- Preliminary exploratory research on the application value of oral and intestinal meta-genomics in predicting subjects' occupations-A case study of the distinction between students and migrant workers.Frontiers in microbiology · 2023Article
- Brain Natriuretic Peptide (BNP) Affects Growth and Stress Tolerance of Representatives of the Human Microbiome,Biology · 2022Article
- The oral microbiome, pancreatic cancer and human diversity in the age of precision medicine.Microbiome · 2022Review
- Standardized studies of the oral microbiome: From technology-driven to hypothesis-driven.iMeta · 2022Review
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human microbiome plays a key role in maintaining host homeostasis and is influenced by age, geography, diet, and other factors. Traditionally, India has an established convention of extended family arrangements wherein three or more generations, bound by genetic relatedness, stay in the same household. In the present study, we have utilized this unique family arrangement to understand the association of age with the microbiome. We characterized stool, oral and skin microbiome of 54 healthy individuals from six joint families by 16S rRNA gene-based metagenomics. In total, 69 (1.03%), 293 (2.68%) and 190 (8.66%) differentially abundant OTUs were detected across three generations in the gut, skin and oral microbiome, respectively. Age-associated changes in the gut and oral microbiome of patrilineal families showed positive correlations in the abundance of phyla Proteobacteria and Fusobacteria, respectively. Genera Treponema and Fusobacterium showed a positive correlation with age while Granulicatella and Streptococcus showed a negative correlation with age in the oral microbiome. Members of genus Prevotella illustrated high abundance and prevalence as a core OTUs in the gut and oral microbiome. In conclusion, this study highlights that precise and perceptible association of age with microbiome can be drawn when other causal factors are kept constant.
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