Evidence map›Paper›PMID 32231102›Full record

ArticleBiomolecules2020

Glycofullerenes Inhibit Particulate Matter Induced Inflammation and Loss of Barrier Proteins in HaCaT Human Keratinocytes.

Chiang-Wen Lee, Yu-Han Su, Yao-Chang Chiang, I-Ta Lee, Sin-Yu Li, Hui-Chun Lee, Lee-Fen Hsu, Yi-Ling Yan, Hsing-Yen Li, Ming-Chun Chen and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 24 citations in OpenAlex.

  1. Protective Effects ofCurrent issues in molecular biology · 2025
    Article
  2. Review
  3. Antioxidant, Anti-Inflammation and Antiaging Activities ofAntioxidants (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Chiang-Wen LeeDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 61363, Taiwan.
Yu-Han SuGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 40227, Taiwan.
Yao-Chang ChiangDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 61363, Taiwan.
I-Ta LeeSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.
Sin-Yu LiDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 61363, Taiwan.
Hui-Chun LeeDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, and Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Technology, Puzi City, Chiayi County 61363, Taiwan.
Lee-Fen HsuDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, and Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Technology, Puzi City, Chiayi County 61363, Taiwan.
Yi-Ling YanDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, and Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Technology, Puzi City, Chiayi County 61363, Taiwan.
Hsing-Yen LiGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 40227, Taiwan.
Ming-Chun ChenGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 40227, Taiwan.
Kuo-Ti PengDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 61363, Taiwan.
Chian-Hui LaiGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 40227, Taiwan.
Chang Gung University of Science and Technology · TWKaohsiung Medical University · TWNational Chung Hsing University · TWChang Gung University · TWMing Chi University of Technology · TWTaipei Medical University · TW

Funding

Chang Gung Medical Research Program Foundation CMRPF6G0081, CMRPF6H0041, CMRPF6H0042, CMRPF6J0051, CMRPF6K0041Chang Gung University of Science Foundation ZRRPF3J0081, ZRRPF6J0011Ministry of Science and Technology, Taiwan 106-2320-B-255-001-, 106-2314-B-255-007-, 107-2113-M-005-014-, 108-2113-M-005-004-,
6 · The paper itself

Abstract

Exposure to particulate matter (PM) has been linked to pulmonary and cardiovascular dysfunctions, as well as skin diseases, etc. PM impairs the skin barrier functions and is also involved in the initiation or exacerbation of skin inflammation, which is linked to the activation of reactive oxygen species (ROS) pathways. Fullerene is a single C

Indexed as

ApoptosisCell LineDermatitisDinoprostoneDynamic Light ScatteringFilaggrin ProteinsFullerenesHumansKeratinocytesMagnetic Resonance SpectroscopyParticle SizeParticulate MatterPhosphorylationProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSpectrophotometry, UltravioletDinoprostoneFilaggrin ProteinsFLG protein, humanFullerenesParticulate MatterProto-Oncogene Proteins c-aktReactive Oxygen Speciesanti-inflammationantioxidantglycofullereneshuman keratinocytesparticulate matterreactive oxygen species

Identifiers

PMID32231102
PMCPMC7225947
OpenAlexW3013339350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.