Evidence map›Paper›PMID 32231090›Full record

ArticleMethods and protocols2020

Exploring Patient Views and Acceptance of Multiparametric Magnetic Resonance Imaging for the Investigation of Suspected Prostate Cancer (the PACT Study): A Mixed-Methods Study Protocol.

Joseph M Norris, Veeru Kasivisvanathan, Clare Allen, Rhys Ball, Alex Freeman, Maneesh Ghei, Alex Kirkham, Hayley C Whitaker, Daniel Kelly, Mark Emberton

Open access · goldAbstract read
In one paragraph

Article in Methods and protocols, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Conspicuity of prostate cancer on multiparametric magnetic resonance imaging: A cross-disciplinary translational hypothesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Joseph M NorrisUCL Division of Surgery and Interventional Science, University College London, London W1W 7TY, UK.ORCID 0000-0003-2294-0303
Veeru KasivisvanathanUCL Division of Surgery and Interventional Science, University College London, London W1W 7TY, UK.ORCID 0000-0002-0832-382X
Clare AllenDepartment of Radiology, University College London Hospitals NHS Foundation Trust, London W1G 8PH, UK.
Rhys BallDepartment of Pathology, University College London Hospitals NHS Foundation Trust, London W1T 4EU, UK.
Alex FreemanDepartment of Pathology, University College London Hospitals NHS Foundation Trust, London W1T 4EU, UK.
Maneesh GheiDepartment of Urology, The Whittington Hospital, Whittington Health NHS Trust, London N19 5NF, UK.
Alex KirkhamDepartment of Radiology, University College London Hospitals NHS Foundation Trust, London W1G 8PH, UK.
Hayley C WhitakerUCL Division of Surgery and Interventional Science, University College London, London W1W 7TY, UK.
Daniel KellySchool of Healthcare Sciences, Cardiff University, Wales CF14 4XN, UK.
Mark EmbertonUCL Division of Surgery and Interventional Science, University College London, London W1W 7TY, UK.ORCID 0000-0003-4230-0338
University College London Hospitals NHS Foundation Trust · GBCardiff University · GBUniversity College London · GBWhittington Hospital · GB

Funding

Medical Research Council MR/M009092/1Medical Research Council MR/S00680X/1
6 · The paper itself

Abstract

backgroundThe introduction of multiparametric magnetic resonance imaging (mpMRI) has improved the diagnosis of suspected prostate cancer, accurately risk-stratifying men before a biopsy. However, pre-biopsy mpMRI represents a significant deviation from the traditional approach of prostate specific antigen testing with subsequent systematic transrectal ultrasound-guided prostate biopsy and we have not yet explored the views of men who experience this new pathway. The purpose of the PACT study (PAtient views and aCceptance of mulTiparametric MRI) is to explore men's perceptions of mpMRI.

methodsPACT will be conducted at teaching hospitals in which mpMRI is central to the prostate cancer diagnostic pathway using a two-phase, mixed-methods, quantitative and qualitative approach. In phase I, men referred with suspected prostate cancer will complete detailed surveys to explore their views on the mpMRI-directed pathway compared to the traditional pathway and on what constitutes 'significant' prostate cancer. In phase II, these themes will be expanded upon with in-depth, semi-structured interviews. Qualitative data will be transcribed and thematically analysed, and quantitative questionnaire responses will be analysed statistically. DISCUSSION: PACT will provide the first detailed insight into patient perceptions on the use and acceptability of mpMRI. Furthermore, results from PACT will help contribute to the resolution of outstanding controversies that surround this technology.

Indexed as

diagnostic pathwaymultiparametric MRIpatient viewsprostate cancerrisk stratification

Identifiers

PMID32231090
PMCPMC7359448
OpenAlexW3014014504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.